2-(4-Chlorophenoxy)-N'-[(1E)-[4-(trifluoromethoxy)phenyl]methylidene]acetohydrazide CAS 868630-56-2
| CAS No. | 868630-56-2 |
| Molecular Formula | C16H12ClF3N2O3 |
| Molecular Weight | 372.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 372.73 g/mol gives 2-(4-Chlorophenoxy)-N'-[(1E)-[4-(trifluoromethoxy)phenyl]methylidene]acetohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(4-Chlorophenoxy)-N'-[(1E)-[4-(trifluoromethoxy)phenyl]methylidene]acetohydrazide (CAS 868630-56-2), a certified reference material (molecular formula C16H12ClF3N2O3, MW 372.73 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-(4-Chlorophenoxy)-N'-[(1E)-[4-(trifluoromethoxy)phenyl]methylidene]acetohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 372.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12ClF3N2O3 |
| Molecular Weight | 372.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenoxy Standards
- 1-(4-Chlorophenoxy)-4-(2,3-dihydro-1H-inden-5-yl)phthalazine (CAS 866138-09-2)
- 1-[6-(4-Chlorophenoxy)hexyl]-3-cyano-2-pyridin-4-ylguanidine (CAS 200484-11-3)
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- 2-(4-Chlorophenoxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile (CAS 338749-45-4)
- 3-(4-(2-Chlorophenoxy)piperidine-1-carboxamido)benzoic acid (CAS 1058702-87-6)
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Recommended Standards
- 2-((1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)methylene)malononitrile (CAS 338409-96-4)
- 2-{[2-Chloro-5-(trifluoromethyl)phenyl]amino}-2-oxoethyl 4-aminobenzoate (CAS 931259-26-6)
- (Z)-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]({[(pyridin-3-yl)methyl]amino})methylidene}amino acetate (CAS 320420-59-5)
- 4-[5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-4,5-dihydro-1,2-oxazol-3-yl]pyrimidin-2-amine (CAS 344277-07-2)
- (203)81Tl (203)Tl 14280-48-9 CHEBI:37802 thallium, isotope of mass 203 thallium-203 (CAS 14280-48-9)
- 848486-92-0 (~13~C_4_)Oxolan-2-one DTXSID50745818 (CAS 848486-92-0)
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- 2-(2-Formylhydrazinylidene)-pentanedioic Acid (CAS 943418-43-7)
- Methyl 3-formyl-5-(methylsulfonyl)-1H-indole-2-carboxylate (CAS 318292-56-7)
- 1,2,5-Trimethyl-4-phenyl-1H-pyrazol-3(2H)-one (CAS 79994-65-3)
- 7-Bromo-9,9-diethyl-N,N-diphenyl-9H-fluoren-2-amine (CAS 202831-64-9)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
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