Bortezomib Impurity 9 CAS 886979-78-8

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.886979-78-8
Molecular FormulaC19H24N4O4
Molecular Weight372.42 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bortezomib Impurity 9 CAS 886979-78-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 372.42 g/mol gives Bortezomib Impurity 9 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Bortezomib Impurity 9 (CAS 886979-78-8), a pharmacopoeial impurity reference standard (molecular formula C19H24N4O4, MW 372.42 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Bortezomib Impurity 9 (C19H24N4O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Bortezomib Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC19H24N4O4
Molecular Weight372.42 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Nitrogen Atoms4

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