Salicylic Acid Impurity 1 CAS 89469-32-9
| CAS No. | 89469-32-9 |
| Molecular Formula | C8H7ClO5S |
| Molecular Weight | 250.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Salicylic Acid Impurity 1 (CAS 89469-32-9) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7ClO5S and a molecular weight of 250.66 g/mol.
Structurally, Salicylic Acid Impurity 1 (C8H7ClO5S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 250.66 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO5S |
| Molecular Weight | 250.66 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1982 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Salicylic Standards
- Salicylic Acid Impurity 27 (CAS 51904-91-7)
- Salicylic Acid Impurity 26 (CAS 83957-15-7)
- Salicylic Acid Impurity 21 (CAS CATO-C4X-190221)
- Salicylic acid Impurity 28 (CAS 32499-37-9)
- Salicylic acid impurity 33 (CAS CATO-C4X-190233)
- Salicylic Acid Impurity 23 (CAS CATO-C4X-190223)
- Salicylic Acid Impurity 34 (CAS CATO-C4X-190234)
- Salicylic acid Impurity 13 (CAS CATO-C4X-190213)
Recommended Standards
- Furosemide EP Impurity C (CAS 3086-91-7)
- Indapamide Impurity 11 (CAS 1856658-28-0)
- Bumetanide Impurity 8 (CAS 25317-76-4)
- Cefaclor Impurity 29 (CAS CATO-C4X-127029)
- Tamoxifen EP Impurity D Oxalate (Mixture of Z and E Isomers) (CAS CATO-C4X-123314)
- Everolimus Impurity 26 (CAS CATO-C4X-112226)
- Ruxolitinib Impurity 135 (CAS CATO-C4X-2058135)
- 7-oxabicyclo[2.2.1]heptane-2-sulfonamide (CAS 1864058-40-1)
- 1-((4-Bromobenzyl)oxy)-2,4-difluorobenzene (CAS 910453-96-2)
- N-(3-Chlorophenyl)-5-piperidin-4-yl-1,3,4-thiadiazole-2-carboxamide (CAS 1217862-31-1)
- tert-Butyl 4-ethynylpiperidine-1-carboxylate (CAS 287192-97-6)
- (3-Nitropyridin-2-yl)methanamine (CAS 1824097-41-7)
- 5-Amino-2-fluoronicotinonitrile (CAS 1260663-78-2)
- Acetyl tetrapeptide-3 (CAS 827306-88-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com