Celecoxib Impurity 67 CAS 910303-54-7
| CAS No. | 910303-54-7 |
| Molecular Formula | C11H9F3O2 |
| Molecular Weight | 230.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Celecoxib Impurity 67 (CAS 910303-54-7) is a certified pharmaceutical impurity reference standard with the molecular formula C11H9F3O2 and a molecular weight of 230.18 g/mol.
Based on its molecular formula C11H9F3O2, Celecoxib Impurity 67 contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 230.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Celecoxib Impurity 67 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9F3O2 |
| Molecular Weight | 230.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Celecoxib Standards
- Celecoxib Impurity 22 (CAS 163266-02-2)
- Celecoxib Impurity 25 (CAS CATO-C4X-104325)
- Celecoxib Impurity 49 (CAS 720-94-5)
- Celecoxib Impurity 57 (CAS CATO-C4X-104357)
- Celecoxib Impurity 59 (CAS CATO-C4X-104359)
- Celecoxib Impurity 11 (CAS 219986-64-8)
- Celecoxib Impurity 54 (CAS 948293-46-7)
- Celecoxib Impurity 1 (CAS 54779-81-6)
Recommended Standards
- Cinacalcet Impurity 96 (CAS CATO-C4X-105996)
- Moxifloxacin Impurity 55 (CAS 53764-99-1)
- 2-(Methylamino)-2-(4-(trifluoromethoxy)phenyl)acetonitrile (CAS 1039814-37-3)
- (4-ethenylphenyl)methyl 2,2,2-tris(fluoranyl)ethanoate 2,2,2-trifluoroacetic acid (4-ethenylphenyl)methyl ester 229956-99-4 A816465 (CAS 229956-99-4)
- Amiodarone Impurity 29 (CAS CATO-C4X-142529)
- Avatrombopag Impurity 143 (CAS 2115508-48-8)
- Rifaximin EP Impurity H (CAS 1210022-90-4)
- Tert-butyl 1,4-thiazepane-4-carboxylate 1,1-dioxide (CAS 1272667-21-6)
- 2-(4-(Phenylamino)butyl)isoindoline-1,3-dione (CAS 500287-57-0)
- (3-(2-Chlorophenyl)-5-methylisoxazol-4-yl)(2-(methylthio)-4,5-dihydro-1H-imidazol-1-yl)methanone (CAS 218457-25-1)
- (3aS,8aS)-4,4,8,8-Tetrakis(3,5-dimethylphenyl)tetrahydro-2,2-dimethyl-6-phenyl-1,3-dioxolo[4,5-e][1,3,2]dioxaphosphepin (CAS 1169835-86-2)
- Tert-butyl 4-(tert-butyl)-3-(hydroxymethyl)-2-methylpiperazine-1-carboxylate (CAS 2366181-82-8)
- Rocuronium Impurity 62 (CAS CATO-C4X-124262)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com