Neratinib Maleate CAS 915942-22-2
| CAS No. | 915942-22-2 |
| Molecular Formula | C30H29ClN6O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 673.12 g/mol gives Neratinib Maleate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Neratinib Maleate (CAS 915942-22-2), molecular formula C30H29ClN6O3C4H4O4 and molecular weight 673.12 g/mol, is a CATO reference standard with documented purity and traceability.
Neratinib Maleate (C30H29ClN6O3C4H4O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C30H29ClN6O3 C4H4O4 |
| Molecular Weight | 673.12 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Neratinib Standards
- Neratinib Impurity 10 (CAS 1144516-13-1)
- Neratinib Impurity 14 (CAS 1144516-14-2)
- Neratinib Impurity 21 (CAS 1144516-15-3)
- Neratinib Impurity 11 (CAS 1144516-16-4)
- Neratinib Impurity 18 (CAS 1144516-17-5)
- Neratinib Impurity 12 (CAS 1144516-18-6)
- Neratinib Impurity 17 (CAS 1144516-19-7)
- Neratinib Impurity 2 (CAS 1144516-20-0)
Recommended Standards
- 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-N-methylethan-1-amine hydrochloride (CAS 473801-85-3)
- (S)-1-(2,4,5-trifluorophenyl)but-3-en-1-amine (CAS 1269949-01-0)
- tert-Butyl 3-((S)-2-amino-N,3-dimethylbutanamido)pyrrolidine-1-carboxylate (CAS 1354024-05-7)
- 2-(4-Iodophenoxy)-4-methoxypyrimidine (CAS 894400-12-5)
- 1,1-difluoro-4-phenylbutan-2-ol 145299-87-2 (CAS 145299-87-2)
- 2-methyl-octahydro-1H-indole (CAS 50669-77-7)
- 3-(5-Methyl-1H-indazol-3-yl)propan-1-amine (CAS 1520881-08-6)
- 2,3-Bis(5-amino-2-chlorophenyl)propanenitrile (CAS 1272756-66-7)
- 3-(1,3-Benzoxazol-2-yl)-4,4,4-trifluoro-3-hydroxybutanoic acid (CAS 1197669-20-7)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
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