Tucatinib Impurity 23 CAS 920966-13-8
| CAS No. | 920966-13-8 |
| Molecular Formula | C8H6ClN3O |
| Molecular Weight | 195.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Tucatinib Impurity 23 (CAS 920966-13-8), a pharmacopoeial impurity reference standard (molecular formula C8H6ClN3O, MW 195.61 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C8H6ClN3O, Tucatinib Impurity 23 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 195.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Tucatinib Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClN3O |
| Molecular Weight | 195.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Tucatinib Standards
- Tucatinib Impurity 22 (CAS 920966-03-6)
- Tucatinib Impurity 48 (CAS CATO-C4X-260548)
- Tucatinib Impurity 66 (CAS CATO-C4X-260566)
- Tucatinib Impurity 6 (CAS CATO-C4X-26056)
- Tucatinib Impurity 29 (CAS CATO-C4X-260529)
- Tucatinib Impurity 42 (CAS CATO-C4X-260542)
- Tucatinib Impurity 43 (CAS CATO-C4X-260543)
- Tucatinib Impurity 41 (CAS CATO-C4X-260541)
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- 4-Chloro-5-fluoro-8-methylquinoline (CAS 1065093-43-7)
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- 3-(Benzyloxy)-5-(chloromethyl)pyridine (CAS 1260663-40-8)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com