Tucatinib Impurity 66 CAS CATO-C4X-260566
| CAS No. | CATO-C4X-260566 |
| Molecular Formula | C10H14N4 |
| Molecular Weight | 190.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tucatinib Impurity 66 (CAS CATO-C4X-260566), a pharmacopoeial impurity reference standard (molecular formula C10H14N4, MW 190.24 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tucatinib Impurity 66 (C10H14N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Tucatinib Impurity 66 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H14N4 |
| Molecular Weight | 190.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Tucatinib Standards
- Tucatinib Impurity 48 (CAS CATO-C4X-260548)
- Tucatinib Impurity 23 (CAS 920966-13-8)
- Tucatinib Impurity 22 (CAS 920966-03-6)
- Tucatinib Impurity 6 (CAS CATO-C4X-26056)
- Tucatinib Impurity 29 (CAS CATO-C4X-260529)
- Tucatinib Impurity 42 (CAS CATO-C4X-260542)
- Tucatinib Impurity 43 (CAS CATO-C4X-260543)
- Tucatinib Impurity 41 (CAS CATO-C4X-260541)
Recommended Standards
- Upadacitinib Impurity 174 (CAS CATO-C4X-2405174)
- Alectinib Impurity 4 (CAS 1256584-72-1)
- Pentoxyverine EP Impurity A (CAS 77-55-4)
- Pemafibrate Impurity 11 (CAS 20852-38-4)
- Dacomitinib Impurity 40 (CAS CATO-C4X-208640)
- Tranilast Impurity 2 (CAS 91920-58-0)
- Acalabrutinib Impurity 7 (CAS CATO-C4X-30557)
- 7-Amino-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 63012-90-8)
- 1-Allyl-2-methoxybenzene (CAS 3698-28-0)
- 1-Ethyl-4-iodo-5-nitro-1h-pyrazole-3-carboxylic acid (CAS 1354706-75-4)
- 3-(2-Imino-4-methyl-6-oxo-3,6-dihydropyrimidin-1(2h)-yl)propanoic acid (CAS 19675-50-4)
- N-Methylpiperazine-1-sulfonamide hydrochloride (CAS 1795394-70-5)
- Bromfenac Impurity 6 (CAS 241496-82-2(free acid))
- Eledoisin Related Peptide (CAS 2990-43-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com