Tucatinib Impurity 43 CAS CATO-C4X-260543
| CAS No. | CATO-C4X-260543 |
| Molecular Formula | C9H11N3 |
| Molecular Weight | 161.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Tucatinib Impurity 43 (C9H11N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Tucatinib Impurity 43 (CAS CATO-C4X-260543) is a certified pharmaceutical impurity reference standard with the molecular formula C9H11N3 and a molecular weight of 161.20 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tucatinib Impurity 43 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11N3 |
| Molecular Weight | 161.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Tucatinib Standards
- Tucatinib Impurity 44 (CAS 197382-76-6)
- Tucatinib Impurity 66 (CAS CATO-C4X-260566)
- Tucatinib Impurity 48 (CAS CATO-C4X-260548)
- Tucatinib Impurity 23 (CAS 920966-13-8)
- Tucatinib Impurity 22 (CAS 920966-03-6)
- Tucatinib Impurity 6 (CAS CATO-C4X-26056)
- Tucatinib Impurity 29 (CAS CATO-C4X-260529)
- Tucatinib Impurity 42 (CAS CATO-C4X-260542)
Recommended Standards
- Rimegepant Impurity 62 (CAS 63031-32-3)
- 2-[2-(2-aminoethylamino)ethylamino]acetic acid (CAS 55682-22-9)
- 2-Methyl-3-phenylacrylamide (CAS 940-27-2)
- Chlorquinaldol impurity 1 (CAS 1649935-12-5)
- Safinamide Impurity 26 (CAS CATO-C4X-159026)
- HISTIDINE Impurity 8 (CAS CATO-C4X-32398)
- Florasulam impurity 50 (CAS CATO-C3D-26050)
- 1-Chloro-4-methylnaphthalene (CAS 17075-39-7)
- 2-Amino-4,5-dichlorobenzonitrile (CAS 28568-04-9)
- 3-Acetylbenzenesulfonamide (CAS 35203-88-4)
- 4-Cyclopentylbut-2-Enenitrile (CAS 1269823-36-0)
- 3-(1-(4-Fluorobenzoyl)-1H-pyrazol-3-yl)-1-phenylpyridazin-4(1H)-one (CAS 318497-98-2)
- Cholecalciferol Impurity 18 (CAS CATO-C4X-158618)
- Urotensin II-Related Peptide (human, mouse, rat) (CAS 342878-90-4)
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