Betamethasone impurity 53 CAS CATO-C4X-143753
| CAS No. | CATO-C4X-143753 |
| Molecular Formula | C23H29FO5 |
| Molecular Weight | 404.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Betamethasone impurity 53 (CAS CATO-C4X-143753, C23H29FO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Betamethasone impurity 53 (C23H29FO5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Betamethasone impurity 53 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H29FO5 |
| Molecular Weight | 404.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone impurity 64 (CAS CATO-C4X-143764)
- Betamethasone Impurity N22 (CAS 116522-68-0)
- Betamethasone impurity 51 (CAS 1184871-61-1)
- Betamethasone impurity 105 (CAS CATO-C4X-1437105)
- Betamethasone Impurity 89 (CAS CATO-C4X-143789)
- Betamethasone Impurity N1 (CAS 910-99-6)
- Betamethasone Impurity 112 (CAS CATO-C4X-1437112)
- Betamethasone Impurity 121 (CAS CATO-C4X-1437121)
Recommended Standards
- Methyl 4-acetamido-3-nitrobenzoate (CAS 6313-39-9)
- 9-Methyl-2-((3-(trifluoromethyl)benzyl)thio)-5H-thiochromeno[4,3-d]pyrimidine (CAS 478246-84-3)
- 5-Bromo-2-[(3-bromobenzyl)oxy]benzoyl chloride (CAS 1160249-97-7)
- (R)-tert-Butyl 4-(2,4-difluoro-5-(2-(methylsulfinyl)ethoxy)phenyl)piperazine-1-carboxylate (CAS 2246609-56-1)
- Dydrogesterone Impurity 19 (CAS 74496-89-2)
- Levodopa Impurity 20 (CAS 33043-37-7)
- Varenicline Impurity C03 (CAS 230615-52-8)
- N-(3-bromobenzyl)butan-2-amine hydrochloride (CAS 1049678-18-3)
- (E)-(2-Methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenyl)-L-alanine (CAS 592543-24-3)
- Crisaborole impurity 116 (CAS CATO-C4X-2021116)
- Daprodustat Impurity 41 (CAS CATO-C4X-240741)
- 1-(2-(6-Amino-2-methylpyridin-3-yl)pyrrolidin-1-yl)ethan-1-one (CAS 1352538-95-4)
- 6-Desamino 6-Chloro Etravirine-13C3 (CAS 1246818-40-5)
- Acetyl decapeptide-3 (CAS 935288-50-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com