Chlorthalidone Impurity 15 CAS 956-92-3
| CAS No. | 956-92-3 |
| Molecular Formula | C14H10ClNO2 |
| Molecular Weight | 259.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 259.69 g/mol gives Chlorthalidone Impurity 15 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Chlorthalidone Impurity 15 (CAS 956-92-3, C14H10ClNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Chlorthalidone Impurity 15 (C14H10ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Chlorthalidone Impurity 15 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H10ClNO2 |
| Molecular Weight | 259.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorthalidone Standards
- Chlorthalidone Impurity N1 (CAS 5543-24-8)
- Chlorthalidone RC 4 (CAS 55275-44-0)
- Chlorthalidone EP Impurity G (CAS 16289-13-7)
- Chlorthalidone RC 3 (CAS 61959-32-8)
- Chlorthalidone impurity 18 (CAS 87177-16-0)
- Chlorthalidone Impuruty 8 (CAS 82875-49-8)
- Chlorthalidone impurity 16 (CAS CATO-C4X-158516)
- Chlorthalidone Impurity 7 (CAS 345930-31-6)
Recommended Standards
- Ziprasidone Impurity 43 (CAS CATO-C4X-124043)
- Pranoprofen Impurity 67 (CAS CATO-C4X-181167)
- tert-Butyl (6-chloro-2-methyl-3-oxo-2,3-dihydropyridazin-4-yl)carbamate (CAS 2680821-04-7)
- Estazolam Impurity 3 (CAS 10352-28-0)
- Penehyclidine Impurity 28 (CAS 3731-38-2)
- Voriconazole Impurity 79 (CAS CATO-C4X-136679)
- Bromfenac Impurity 62 (CAS CATO-C4X-200262)
- Orexin B (human) (CAS 205640-91-1)
- 3-Iodo-6-methyl-4H-chromen-4-one (CAS 341528-94-7)
- Methyl 2-(4-fluorophenyl)-5-hydroxybenzofuran-3-carboxylate (CAS 691856-96-9)
- (1R)-1-(3,5-dibromophenyl)ethane-1,2-diamine (CAS 1212864-54-4)
- 4-(Chloromethyl)-2-(oxolan-2-yl)-1,3-thiazole (CAS 1423028-25-4)
- 4-{6-chloro-2-methyl-3H-imidazo[4,5-b]pyridin-3-yl}piperidine (CAS 1266768-94-8)
- Semaglutide impurity 31 (CAS CATO-C4X-222631)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com