(4-(Difluoromethoxy)-3-methylphenyl)boronic acid CAS 958451-72-4
| CAS No. | 958451-72-4 |
| Molecular Formula | C8H9BF2O3 |
| Molecular Weight | 201.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, (4-(Difluoromethoxy)-3-methylphenyl)boronic acid is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 201.96 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(4-(Difluoromethoxy)-3-methylphenyl)boronic acid (CAS 958451-72-4) is a high-purity analytical reference standard with the molecular formula C8H9BF2O3 and a molecular weight of 201.96 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (4-(Difluoromethoxy)-3-methylphenyl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9BF2O3 |
| Molecular Weight | 201.96 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
- (4-(Difluoromethoxy)-2-methylphenyl)boronic acid (CAS 514206-39-4)
- [2-(Difluoromethoxy)-3-methylphenyl]boronic acid (CAS 958451-78-0)
- [2-(Difluoromethoxy)-5-methylphenyl]boronic acid (CAS 958451-75-7)
- 3-(Difluoromethoxy)-4-methylphenylboronic acid (CAS 958451-74-6)
- 2-(Difluoromethoxy)-4-methoxybenzaldehyde (CAS 1247613-99-5)
- 3-(difluoromethoxy)-4-methylbenZoic acid (CAS 1249751-97-0)
- 4-(Difluoromethoxy)-3-methylbenzoic acid (CAS 1427373-23-6)
- 3-(Difluoromethoxy)-5-methylbenzoic acid (CAS 1427403-26-6)
Recommended Standards
- (5-Ethoxy-2,4-difluorophenyl)boronic acid (CAS 900175-12-4)
- (4-(2,2-Difluoroethoxy)phenyl)boronic acid (CAS 958453-65-1)
- (3-(2,2-Difluoroethoxy)phenyl)boronic acid (CAS 958452-33-0)
- (2-Ethoxy-4,5-difluorophenyl)boronic acid (CAS 870778-87-3)
- 2-((3-(Trifluoromethyl)benzyl)thio)ethanamine (CAS 143627-50-3)
- (4-Methyl-1H-pyrazol-3-yl)boronic acid (CAS 1562244-77-2)
- (4-Carboxyphenyl)diphenylphosphine 2129-31-9 4-(Diphenylphosphino)benzoic acid Diphenyl(p-carboxyphenyl) phosphine p-(Diphenylphosphino)benzoic acid (CAS 2129-31-9)
- Furin Inhibitor II (CAS 673202-67-0)
- 2-(5-Fluoro-2-methyl-1H-indol-3-yl)-ethylamine hydrochloride (CAS 1079-45-4)
- (4,5-Difluoro-2-methoxyphenyl)methanol (CAS 886761-72-4)
- 2-{8-oxatricyclo[7.4.0.0,2,7]trideca-1(9),2,4,6-tetraen-4-yloxy}acetic acid (CAS 34855-08-8)
- Ethyl 5-(4-chlorophenyl)-2,4-dioxoimidazolidine-1-carboxylate (CAS 18755-74-3)
- Ethyl 4-amino-3,5-dichlorobenzoate (CAS 74878-31-2)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
Why CATO?
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