rac-Carbidopa EP Impurity F HCl CAS 96115-88-7
| CAS No. | 96115-88-7 |
| Molecular Formula | C12H18N2O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of rac-Carbidopa EP Impurity F HCl (C12H18N2O4HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
rac-Carbidopa EP Impurity F HCl (CAS 96115-88-7) is a certified pharmaceutical impurity reference standard with the molecular formula C12H18N2O4HCl and a molecular weight of 290.74 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), rac-Carbidopa EP Impurity F HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H18N2O4 HCl |
| Molecular Weight | 290.74 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related rac Standards
- Carbidopa Impurity 36 (CAS 1026009-73-3)
- Carbidopa EP Impurity B Hydrochloride (CAS 115054-62-1)
- rac-Carbidopa EP Impurity I (CAS 1246819-09-9)
- (S)-(-)-Carbidopa-d3 H2O (ring-d3) (CAS 1276197-58-0)
- Carbidopa-d3 (CAS 1276732-89-8)
- Carbidopa EP Impurity H (CAS 1361017-74-4)
- (S)-(-)-Carbidopa-d5 (CAS 1426174-03-9)
- Carbidopa EP Impurity F (CAS 1458640-32-8)
Recommended Standards
- Tamsulosin Impurity 64 (CAS CATO-C4X-118764)
- Sildenafil Impurity 294 (CAS 200575-17-3)
- Finerenone Impurity 72 (CAS CATO-C4X-288072)
- 9-Azabicyclo[6.1.0]nonane (CAS 286-61-3)
- 1,1-Dimethylethyl N-(3-cyclopropyl-3-hydroxycyclobutyl)-N-methylcarbamate (CAS 2770963-91-0)
- 2-Bromo-5-methylbenzamide (CAS 101421-61-8)
- Tert-butyl (S)-7-amino-5-thia-2-azaspiro[3.4]Octane-2-carboxylate 5,5-dioxide (CAS 2381705-16-2)
- 1-Ethyl-2-methyl-1H-indol-5-amine (CAS 878733-38-1)
- (R)-2-(methylamino)-2-(4-(trifluoromethoxy)phenyl)ethan-1-ol (CAS 1336092-54-6)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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