Baclofen Impurity 81 CAS CATO-C4X-101281
| CAS No. | CATO-C4X-101281 |
| Molecular Formula | C16H16ClNO4 |
| Molecular Weight | 321.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Baclofen Impurity 81.
Baclofen Impurity 81 (CAS CATO-C4X-101281) is a certified pharmaceutical impurity reference standard with the molecular formula C16H16ClNO4 and a molecular weight of 321.76 g/mol.
Structurally, Baclofen Impurity 81 (C16H16ClNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 321.76 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16ClNO4 |
| Molecular Weight | 321.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Baclofen Standards
- Baclofen Impurity 60 (CAS CATO-C4X-101260)
- Baclofen Impurity 57 (CAS CATO-C4X-101257)
- Baclofen Impurity 61 (CAS CATO-C4X-101261)
- Baclofen Impurity 58 (CAS CATO-C4X-101258)
- Baclofen Impurity 84 (CAS CATO-C4X-101284)
- Baclofen Impurity 36 (CAS CATO-C4X-101236)
- Baclofen Impurity 48 (CAS CATO-C4X-101248)
- Baclofen Impurity 49 (CAS CATO-C4X-101249)
Recommended Standards
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- N-(3-Chlorophenyl)-2-cyano-3-(1H-indol-3-yl)acrylamide (CAS 357617-74-4)
- Midecamycin Impurity 21 (CAS CATO-C4X-312221)
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- 5-Chloro-N-(3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)thiophene-2-carboxamide (CAS 865162-36-3)
- 4-Acryloylbenzoic acid methyl ester (CAS 187401-48-5)
- 2-(4-formyl-1H-1,2,3-triazol-1-yl)acetamide (CAS 1496575-42-8)
- N-((4-Nitrophenyl)thio)acetamide (CAS 39549-16-1)
- 6-(piperidin-1-yl)pyrimidine-4-carboxylic acid hydrochloride (CAS 1803589-77-6)
- Methyl 2-(3-fluoro-5-nitrophenyl)acetate (CAS 1338367-29-5)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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