Paroxetine Hydrochloride Hemihydrate EP Impurity C HCl CAS CATO-C4X-10353
| CAS No. | CATO-C4X-10353 |
| Molecular Formula | C21H25NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Paroxetine Hydrochloride Hemihydrate EP Impurity C HCl (CAS CATO-C4X-10353) is a certified pharmaceutical impurity reference standard with the molecular formula C21H25NO4HCl and a molecular weight of 391.89 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Paroxetine Hydrochloride Hemihydrate EP Impurity C HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 391.89 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H25NO4 HCl |
| Molecular Weight | 391.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 43 (CAS 100332-20-5)
- Paroxetine EP Impurity G HCl (CAS 1012886-75-7)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine EP impurity C (CAS 105813-14-7)
- Paroxetine HCl EP Impurity C (CAS 105813-14-7(free base))
- Paroxetine EP Impurity F HCl (CAS 105813-39-6)
- Paroxetine Impurity 47 (CAS 105813-40-9)
Recommended Standards
- Fosaprepitant Impurity 50 (CAS CATO-C4X-116850)
- Mebeverine EP Impurity B HCl (CAS 93963-24-7)
- Valsartan Impurity 65 (CAS CATO-C4X-105765)
- [6-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyridin-3-yl]methanamine (CAS 1394116-51-8)
- 2-(4-Fluorophenyl)-2h-1,2,3-triazole-4-carboxylic acid (CAS 833-60-3)
- benzothiophene-6-carboxylic acid (CAS 6179-26-6)
- 1-Amino-4-(2-hydroxyethyl)piperazine 2-(4-aminopiperazin-1-yl)ethanol 3973-70-4 (CAS 3973-70-4)
- (3,5-Bis((3,5-dimethoxybenzyl)oxy)phenyl)methanol (CAS 176650-92-3)
- Methyl 7-iodoheptanoate (CAS 38315-25-2)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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