Paroxetine HCl Anhydrous EP Impurity E（and enantiomer） CAS CATO-C4X-103533
| CAS No. | CATO-C4X-103533 |
| Molecular Formula | C19H20FNO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 365.83 g/mol gives Paroxetine HCl Anhydrous EP Impurity E（and enantiomer） distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Paroxetine HCl Anhydrous EP Impurity E（and enantiomer） (CAS CATO-C4X-103533) is a certified pharmaceutical impurity reference standard with the molecular formula C19H20FNO3HCl and a molecular weight of 365.83 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Paroxetine HCl Anhydrous EP Impurity E（and enantiomer） is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 365.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Paroxetine HCl Anhydrous EP Impurity E（and enantiomer） meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H20FNO3 HCl |
| Molecular Weight | 365.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Paroxetine Standards
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 43 (CAS 100332-20-5)
- Paroxetine EP Impurity G HCl (CAS 1012886-75-7)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine EP impurity C (CAS 105813-14-7)
- Paroxetine HCl EP Impurity C (CAS 105813-14-7(free base))
- Paroxetine EP Impurity F HCl (CAS 105813-39-6)
- Paroxetine Impurity 47 (CAS 105813-40-9)
Recommended Standards
- Mianserin Impurity 65 (CAS CATO-C4X-136965)
- Uridine Impurity 7 (CAS CATO-C4X-23347)
- Cefuroxime Sodium EP Impurity B (CAS 39685-31-9)
- Halcinonide (CAS 3093-35-4)
- tert-butyl 2H,4H,5H,6H,7H-pyrazolo[4,3-b]pyridine-4-carboxylate (CAS 1393845-78-7)
- 5-(Aminomethyl)-4-benzyl-1,2,4-triazole-3-thiol, N-BOC protected (CAS 306935-43-3)
- Estradiol Valerate EP Impurity (CAS 1313382-26-1)
- 3-Chloro-2-hydroxy-5-nitropyridine (CAS 22353-38-4)
- Hydroquinone Impurity 8 (CAS CATO-C4X-25988)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
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