Paroxetine HCl Anhydrous EP Impurity J CAS CATO-C4X-103534

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-103534
Molecular FormulaC25H24FNO3
Molecular Weight405.46 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Paroxetine HCl Anhydrous EP Impurity J CAS CATO-C4X-103534 chemical structure

Description

CATO supplies Paroxetine HCl Anhydrous EP Impurity J (CAS CATO-C4X-103534), a pharmacopoeial impurity reference standard (molecular formula C25H24FNO3, MW 405.46 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C25H24FNO3, Paroxetine HCl Anhydrous EP Impurity J contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 405.46 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC25H24FNO3
Molecular Weight405.46 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing
Nitrogen Atoms1

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