Sofosbuvir Impurity 71 CAS CATO-C4X-105271
| CAS No. | CATO-C4X-105271 |
| Molecular Formula | C23H31ClN3O8P |
| Molecular Weight | 543.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Sofosbuvir Impurity 71 (C23H31ClN3O8P) is characterized by a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Sofosbuvir Impurity 71 (CAS CATO-C4X-105271) is a certified pharmaceutical impurity reference standard with the molecular formula C23H31ClN3O8P and a molecular weight of 543.93 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sofosbuvir Impurity 71 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H31ClN3O8P |
| Molecular Weight | 543.93 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir Ph.Int Impurity B(Chloro Sofosbuvir) (CAS 1496552-51-2)
- Sofosbuvir Impurity 10 (CAS 863329-63-9)
- Sofosbuvir D6 (CAS 1868135-06-1)
- Sofosbuvir-13C-d3 (CAS 2070009-25-3)
- Sofosbuvir Impurity 103 (CAS CATO-C4X-1052103)
- Sofosbuvir (CAS 1190307-88-0)
- Sofosbuvir Impurity 22 (CAS 1190308-01-0)
- Sofosbuvir Impurity 23 (CAS CATO-C4X-105223)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com