Empagliflozin Impurity 131 CAS CATO-C4X-1065131
| CAS No. | CATO-C4X-1065131 |
| Molecular Formula | C23H27ClO7 |
| Molecular Weight | 450.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Empagliflozin Impurity 131 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Empagliflozin Impurity 131 (CAS CATO-C4X-1065131) is a certified pharmaceutical impurity reference standard with the molecular formula C23H27ClO7 and a molecular weight of 450.91 g/mol.
Structurally, Empagliflozin Impurity 131 (C23H27ClO7) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 450.91 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H27ClO7 |
| Molecular Weight | 450.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin impurity 02 (CAS 1620758-31-7&1620758-32-8)
- Empagliflozin (CAS 864070-44-0)
- Empagliflozin Impurity 1 (CAS 864070-43-9)
- Empagliflozin Impurity 10 (CAS 2452301-42-5)
- Empagliflozin Impurity 117 (CAS CATO-C4X-1065117)
- Empagliflozin Impurity 118 (CAS CATO-C4X-1065118)
- Empagliflozin Impurity 13 (CAS CATO-C4X-106513)
- Empagliflozin Impurity 137 (CAS CATO-C4X-1065137)
Recommended Standards
- Empagliflozin Impurity 16 (CAS 1620758-32-8)
- Empagliflozin impurity 186 (CAS 2452301-28-7)
- Empagliflozin impurity 196 (CAS CATO-C4X-1065196)
- Empagliflozin impurity 197 (CAS CATO-C4X-1065197)
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