Empagliflozin impurity 226 CAS CATO-C4X-1065226
| CAS No. | CATO-C4X-1065226 |
| Molecular Formula | C17H14BrClO3 |
| Molecular Weight | 381.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C17H14BrClO3, Empagliflozin impurity 226 contains a steroid core, a hydroxyl group, an ether linkage, chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 381.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Empagliflozin impurity 226 (CAS CATO-C4X-1065226) is a certified pharmaceutical impurity reference standard with the molecular formula C17H14BrClO3 and a molecular weight of 381.65 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Empagliflozin impurity 226 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H14BrClO3 |
| Molecular Weight | 381.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 104 (CAS 915095-84-0)
- Empagliflozin impurity 182 (CAS 915095-83-9)
- Empagliflozin impurity 231 (CAS 1637561-86-4)
- Empagliflozin impurity 259 (CAS CATO-C4X-1065259)
- Empagliflozin Impurity 276 (CAS CATO-C4X-1065276)
- Empagliflozin Impurity 277 (CAS CATO-C4X-1065277)
- Empagliflozin Impurity 279 (CAS CATO-C4X-1065279)
- Empagliflozin impurity 194 (CAS CATO-C4X-1065194)
Recommended Standards
- 284686-20-0 N-[5-Bromo-2-(cyclopropylamino)-4-methyl-3-pyridinyl]-2-chloro-3-pyridinecarboxamide (CAS 284686-20-0)
- Ethyl 2-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)hydrazinyl)-3,3,3-trifluoro-2-hydroxypropanoate (CAS 400074-12-6)
- N'-(4-Bromobenzylidene)-2-(4-chloro-2-methylphenoxy)acetohydrazide (CAS 329049-30-1)
- ((2R,3S,4R,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 21466-01-3)
- Etelcalcetide Impurity 40 (CAS CATO-C4X-324740)
- Dapoxetine Impurity 104 (CAS 1346603-24-4(free base))
- Plerixafor Impurity 19 (CAS CATO-C4X-113319)
- 16-Nitroanthra[9,1,2-cde]benzo[rst]pentaphene-5,10-dione (CAS 128-60-9)
- 5-(4-Methoxyphenyl)-2H-tetrazole (CAS 6926-51-8)
- Methyl 2-(4-ethoxyphenyl)-2-hydroxyacetate (CAS 1249819-89-3)
- (R)-1-amino-2,3-dihydro-1H-inden-5-ol (CAS 1228571-48-9)
- 2-Cyano-N-(3,4-dimethylphenyl)acetamide 24522-42-7 8242AD C11H12N2O (CAS 24522-42-7)
- (3AS,4S,6R,7R,7aS)-4-(benzyloxy)-2,2,6-trimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-7-ol (CAS 68124-06-1)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
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