Empagliflozin Impurity 276 CAS CATO-C4X-1065276
| CAS No. | CATO-C4X-1065276 |
| Molecular Formula | C18H18BrClO2 |
| Molecular Weight | 381.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Empagliflozin Impurity 276 (CAS CATO-C4X-1065276), a certified reference material (molecular formula C18H18BrClO2, MW 381.69 g/mol) for analytical method development and quality control.
Empagliflozin Impurity 276 (C18H18BrClO2) contains a steroid core, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18BrClO2 |
| Molecular Weight | 381.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 277 (CAS CATO-C4X-1065277)
- Empagliflozin Impurity 279 (CAS CATO-C4X-1065279)
- Empagliflozin Impurity 104 (CAS 915095-84-0)
- Empagliflozin impurity 182 (CAS 915095-83-9)
- Empagliflozin impurity 226 (CAS CATO-C4X-1065226)
- Empagliflozin impurity 231 (CAS 1637561-86-4)
- Empagliflozin impurity 259 (CAS CATO-C4X-1065259)
- Empagliflozin impurity 194 (CAS CATO-C4X-1065194)
Recommended Standards
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- Miconazole EP Impurity I (CAS 47363-37-1)
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- Bexagliflozin Impurity 9 (CAS 1118567-45-5)
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- 6-Bromo-5-(difluoromethyl)-2-(trifluoromethyl)pyridin-3-ol (CAS 1806865-58-6)
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- 4-{[4-(hydroxymethyl)piperidin-1-yl]carbonyl}-1-methyl-1,2-dihydropyridin-2-one (CAS 1179886-87-3)
- ethyl 2-[(3-amino-1,1,1-trifluoropropan-2-yl)sulfanyl]acetate hydrochloride (CAS 2060008-56-0)
- Methyl 4-chloro-2-(2,3-dihydro-1H-1,3-benzodiazol-2-ylidene)-3-oxobutanoate (CAS 726151-59-3)
- 9H-Fluoren-9-ylmethyl 4-(1-oxo-3-buten-1-yl)-1-piperazinecarboxylate (CAS 876728-43-7)
- 2-Ethyl-2-methylcyclopropane-1-carboxylic acid (CAS 28034-84-6)
- 2-(2,4-Difluorophenyl)-2-methylpropanoic acid (CAS 920501-67-3)
- Semaglutide impurity 68 (CAS CATO-C4X-222668)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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