Erlotinib Impurity 14 CAS CATO-C4X-106914
| CAS No. | CATO-C4X-106914 |
| Molecular Formula | C25H29N3O5 |
| Molecular Weight | 451.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Erlotinib Impurity 14 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Erlotinib Impurity 14 (CAS CATO-C4X-106914, C25H29N3O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Erlotinib Impurity 14 (C25H29N3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Erlotinib Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H29N3O5 |
| Molecular Weight | 451.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Erlotinib Standards
- Erlotinib Impurity 5 (CAS 328528-74-1)
- Erlotinib Impurity 48 (CAS 2055840-54-3)
- ErlotiniB impurity 37 (CAS CATO-C4X-106937)
- Erlotinib Impurity 7 (CAS 882420-21-5)
- Erlotinib impurity 137 (CAS 1318599-96-0)
- Erlotinib impurity 139 (CAS 2218487-28-4)
- Erlotinib Impurity 15 (CAS CATO-C4X-106915)
- Erlotinib Impurity 91 (CAS 1354727-63-1)
Recommended Standards
- (3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(1-naphthyl)butanoic acid (3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-(1-naphthyl)butyric acid (3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-naphthalen-1-yl-butanoic acid (3S)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-naphthalen-1-ylbutanoic acid (3S)-3-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-(1-naphthalenyl)butanoic acid 270063-38-2 Fmoc-(S)-3-Amino-4-(1-naphthyl)-butyric acid (CAS 270063-38-2)
- Mycophenolate Impurity 23 (CAS CATO-C4X-151523)
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(cyclohexyloxy)-5-oxopentanoic acid 204251-25-2 (CAS 204251-25-2)
- Acetylcysteine Impurity 75 (CAS CATO-C4X-153275)
- Cinnarizine EP Impurity D (CAS 1415587-79-9)
- Isavuconazole impurity 75 (CAS CATO-C4X-1236175)
- Tafluprost Impurity 16 (CAS 209861-01-8)
- 2-Ethyl-3,4-dihydronaphthalen-1(2H)-one (CAS 21568-62-7)
- Piperidine-1-carboximidamide (CAS 4705-39-9)
- 2-Cyclopropyl-4-formylbenzonitrile (CAS 2830620-90-9)
- 5-Cyclopropoxy-2-ethyl-4-(methylthio)pyridine (CAS 1243369-75-6)
- Ethyl pyrrolidin-3-ylcarbamate (CAS 117258-69-2)
- 3-tert-butyl-[1,2,4]triazolo[4,3-a]pyridine-6-carboxylic acid (CAS 1250541-35-5)
- Anxiety Peptide (CAS 95237-86-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com