Tenofovir disoproxil Impurity 80 CAS CATO-C4X-107680
| CAS No. | CATO-C4X-107680 |
| Molecular Formula | C13H22N5O4P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tenofovir disoproxil Impurity 80 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Tenofovir disoproxil Impurity 80 (CAS CATO-C4X-107680), a pharmacopoeial impurity reference standard (molecular formula C13H22N5O4PC4H4O4, MW 459.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Tenofovir disoproxil Impurity 80 (C13H22N5O4PC4H4O4) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H22N5O4P C4H4O4 |
| Molecular Weight | 459.40 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Amlodipine Impurity 132 (CAS CATO-C4X-1095132)
- Nifekalant impurity 2 (CAS CATO-C4X-27972)
- iotropium Bromide Impurity 12 (CAS 588-63-6)
- Methyl 5-(3-acetylphenyl)-2-fluorobenzoate (CAS 1820649-52-2)
- (3-Chloro-4-fluorophenyl)(4-((2,5-dihydro-1H-pyrrol-1-yl)methyl)phenyl)methanone (CAS 898764-34-6)
- 5-Chloro-2-((2S,6R)-2,6-dimethylmorpholino)benzaldehyde (CAS 1241675-81-9)
- 2-((2-((Tert-butoxycarbonyl)amino)-3-ethoxy-3-oxopropyl)thio)acetic acid (CAS 1100755-69-8)
- 2,2-dimethylbutanenitrile (CAS 20654-46-0)
- N-[(1E)-{[(2-bromophenyl)methoxy]imino}methyl]-2-(4-chlorophenyl)-2-[3-(trifluoromethyl)quinoxalin-2-yl]acetamide (CAS 338391-66-5)
- Peptide Impurity 28 (CAS 1350456-64-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com