Tofacitinib Impurity 233 CAS CATO-C4X-1079233
| CAS No. | CATO-C4X-1079233 |
| Molecular Formula | C11H19N5 |
| Molecular Weight | 221.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tofacitinib Impurity 233.
As a process- or degradation-related impurity, Tofacitinib Impurity 233 (CAS CATO-C4X-1079233, C11H19N5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Tofacitinib Impurity 233 (C11H19N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 221.30 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tofacitinib Impurity 233 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H19N5 |
| Molecular Weight | 221.30 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Tofacitinib Standards
- Tofacitinib Impurity 182 (CAS 1053228-28-6)
- Tofacitinib Impurity 218 (CAS CATO-C4X-1079218)
- Tofacitinib Impurity 198 (CAS CATO-C4X-1079198)
- Tofacitinib Impurity 126 (CAS 384338-23-2)
- Tofacitinib Impurity 208 (CAS 1638499-31-6)
- Tofacitinib Impurity 57 (CAS 477600-70-7)
- Tofacitinib Impurity 83 (CAS 1638499-33-8)
- Tofacitinib Impurity 144 (CAS 2091669-67-7)
Recommended Standards
- Ethyl 4-(tert-butylamino)benzoate (CAS 36171-08-1)
- Ivabradine Impurity 65 (CAS 2387117-59-9)
- 2-[(3-Methoxyphenoxy)methyl]piperidine 4100AF 946727-56-6 C13H19NO2 (CAS 946727-56-6)
- Ivabradine impurity 91 (CAS CATO-C4X-111991)
- Fexofenadine impurity 43 (CAS CATO-C4X-179443)
- Sepiapterin Impurity 24-D3 (CAS 2747956-15-4)
- Dl-Lysine Acetylsalicylate EP Impurity J (CAS CATO-C4X-22115)
- N-(4-Methoxybenzyl)piperidin-4-amine (CAS 1183259-99-5)
- 1,3-Bis(hydroxymethyl)imidazolidine-2-thione (CAS 15534-95-9)
- Sodium Cromoglicate Impurity C51 (CAS 16130-17-9)
- Ethyl 2,6-difluoro-4-nitrophenylacetate (CAS 1803788-12-6)
- 3-Amino-n-(4,5-dihydro-3h-pyrrol-2-yl)-benzenesulfonamide (CAS 379255-71-7)
- 1-(5-Cyclopropylisoxazol-4-yl)-N-methylmethanamine (CAS 1497089-86-7)
- 110207-62-0 Acetyl-Cholecystokinin Octapeptide (2-8) (sulfated) MFCD00133565 (CAS 110207-62-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com