Rivaroxaban Impurity 53 CAS CATO-C4X-109053
| CAS No. | CATO-C4X-109053 |
| Molecular Formula | C18H22ClN3O5S |
| Molecular Weight | 427.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Rivaroxaban Impurity 53 (C18H22ClN3O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 427.90 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Rivaroxaban Impurity 53 (CAS CATO-C4X-109053), a pharmacopoeial impurity reference standard (molecular formula C18H22ClN3O5S, MW 427.90 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rivaroxaban Impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H22ClN3O5S |
| Molecular Weight | 427.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 145 (CAS CATO-C4X-1090145)
- Rivaroxaban Impurity N45 (CAS 2512215-49-3)
- Rivaroxaban Impurity 165 (CAS CATO-C4X-1090165)
- Rivaroxaban Impurity 160 (CAS CATO-C4X-1090160)
- Rivaroxaban impurity 167 (CAS CATO-C4X-1090167)
- Rivaroxaban Impurity 177 (CAS CATO-C4X-1090177)
- Rivaroxaban Impurity 183 (CAS CATO-C4X-1090183)
- Rivaroxaban Impurity 186 (CAS CATO-C4X-1090186)
Recommended Standards
- (rac-cis)-Z-Bifenthrin-d5 (CAS CATO-CCPD103490)
- Isopropyl 2-amino-4-(2-chlorophenyl)-5-oxo-4H,5H-thiochromeno[4,3-b]pyran-3-carboxylate (CAS 939889-15-3)
- Ethyl 5-acetyl-2-(2-chlorobenzamido)-4-phenylthiophene-3-carboxylate (CAS 333774-40-6)
- 2-(4-Chlorophenyl)-2-oxoethyl 1-butyl-6-oxo-2-phenylpiperidine-3-carboxylate (CAS 477890-10-1)
- Lusutrombopag Impurity 34 (CAS CATO-C4X-208434)
- Sulfadimethoxine EP Impurity B (CAS 555-25-9)
- Irinotecan Impurity 51 (CAS 2944102-98-9)
- Ethyl4-(1,3-dioxoisoindolin-2-yl)-3-oxobutanoate (CAS 13855-80-6)
- tert-Butyl-d9 Methyl Ether (CAS 1219795-06-8)
- 4-{2-[(4-Methylbenzyl)oxy]ethyl}piperidinehydrochloride (CAS 1220018-03-0)
- 4-(2-(Methylamino)ethoxy)aniline (CAS 26179-80-6)
- 3-(4-Benzylpiperidin-1-yl)propan-1-amine (CAS 24157-18-4)
- 4-[2-(methylsulfanyl)-1h-imidazol-1-yl]benzoic acid (CAS 1146290-23-4)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
Why CATO?
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