Amlodipine impurity 128 CAS CATO-C4X-1095128
| CAS No. | CATO-C4X-1095128 |
| Molecular Formula | C26H37ClN2O10 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Amlodipine impurity 128 (CAS CATO-C4X-1095128), a pharmacopoeial impurity reference standard (molecular formula C26H37ClN2O10HCl, MW 609.49 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Amlodipine impurity 128 (C26H37ClN2O10HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 609.49 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H37ClN2O10 HCl |
| Molecular Weight | 609.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine Impurity N32 (CAS 103094-30-0)
- (R)-Amlodipine (CAS 103129-81-3)
- Amlodipine (S)-Isomer (CAS 103129-82-4)
- Amlodipine Impurity N5 (CAS 107812-86-2)
- Amlodipine Impurity N2 (CAS 111429-90-4)
- Amlodipine Besylate (CAS 111470-99-6)
- Amlodipine Impurity N4 (CAS 113994-36-8)
- Amlodipine Impurity 38 (CAS 113994-37-9)
Recommended Standards
- Omeprazole Impurity 45 (CAS 101341-68-8)
- Imatinib Impurity 34 (CAS 765269-29-2)
- Rivaroxaban Impurity 55 (CAS 1257527-98-2)
- 3-Oxocyclohex-1-en-1-yl trifluoromethanesulfonate (CAS 109459-28-1)
- Dichloro[rel-[N(S)]-N-[2-[(R)-methylthio-κS]ethyl]-4-morpholineethanamine-κNN4,κN4](triphenylphosphine)ruthenium(II) (CAS 1799824-01-3)
- (2R,3R,4R,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3-ethynyl-5-(hydroxymethyl)oxolane-3,4-diol (CAS 1044589-82-3)
- 2,2-Diphenylethenamine (CAS 947-90-0)
- tert-Butyl 3-Aminobenzoate (CAS 92146-82-2)
- n-((5-Bromothiophen-2-yl)methyl)-3-ethoxypropan-1-amine (CAS 871805-12-8)
- Semaglutide impurity 01 (CAS 1998701-31-7)
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