Amlodipine Impurity 38 CAS 113994-37-9
| CAS No. | 113994-37-9 |
| Molecular Formula | C19H23ClN2O5 |
| Molecular Weight | 394.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Amlodipine Impurity 38 (C19H23ClN2O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Amlodipine Impurity 38 (CAS 113994-37-9), a pharmacopoeial impurity reference standard (molecular formula C19H23ClN2O5, MW 394.85 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Amlodipine Impurity 38 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H23ClN2O5 |
| Molecular Weight | 394.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amlodipine Standards
- Amlodipine Besylate EP Impurity F (CAS 140171-66-0)
- Amlodipine Impurity N21 (CAS 2170111-18-7)
- Amlodipine Impurity N20 (CAS 2170104-02-4)
- Amlodipine Impurity 76 (CAS CATO-C4X-109576)
- Amlodipine Impurity N1 (CAS 194472-27-0)
- Amlodipine Impurity 30 (CAS 496024-43-2)
- Amlodipine Impurity 60 (CAS 949155-13-9)
- Amlodipine Impurity 78 (CAS CATO-C4X-109578)
Recommended Standards
- NLX-101 (CAS 635323-95-4)
- Benzyl N-({4-[(4-chlorophenyl)carbamoyl]phenyl}methyl)carbamate (CAS 477847-75-9)
- 6-Chloro-1-((4-methoxybenzyl)oxy)-2-(4-methoxyphenyl)-1H-benzo[d]imidazole (CAS 282523-23-3)
- Empagliflozin Impurity N6 (CAS 333359-90-3)
- Vonoprazan Impurity 4 (CAS 1807642-39-2)
- Hydroxychloroquine Impurity 45 (CAS CATO-C4X-183545)
- Tolvaptan Impurity 51 (CAS CATO-C4X-195551)
- 4-Fluorobenzo[d]thiazole-2(3H)-thione (CAS 154327-24-9)
- 4-(Aminomethyl)-3-(difluoromethyl)pyridin-2-ol (CAS 1805319-03-2)
- Sodium (S)-2-oxo-3-(3-oxo-1-phenylbutyl)-2H-chromen-4-olate (CAS 5543-79-3)
- (2,5-Difluoro-4-isopropoxyphenyl)methanol (CAS 2121514-71-2)
- Acipimox Impurity 1 (CAS 5521-55-1)
- N-[[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]pyridazine-3-carboxamide (CAS 2246605-61-6)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com