Amlodipine Impurity 44 CAS CATO-C4X-109544
| CAS No. | CATO-C4X-109544 |
| Molecular Formula | C22H30ClN3O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Amlodipine Impurity 44 (CAS CATO-C4X-109544, C22H30ClN3O6C4H4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C22H30ClN3O6C4H4O4, Amlodipine Impurity 44 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 584.02 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C22H30ClN3O6 C4H4O4 |
| Molecular Weight | 584.02 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >80% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amlodipine Standards
- Amlodipine Impurity N32 (CAS 103094-30-0)
- (R)-Amlodipine (CAS 103129-81-3)
- Amlodipine (S)-Isomer (CAS 103129-82-4)
- Amlodipine Impurity N5 (CAS 107812-86-2)
- Amlodipine Impurity N2 (CAS 111429-90-4)
- Amlodipine Besylate (CAS 111470-99-6)
- Amlodipine Impurity N4 (CAS 113994-36-8)
- Amlodipine Impurity 38 (CAS 113994-37-9)
Recommended Standards
- Pinaverium Bromide Impurity 15 (CAS 4747-61-9)
- Flurbiprofen Impurity 8 (CAS 542-10-9)
- Irbesartan Impurity 20 (CAS 906474-58-6)
- 4-Nitroaniline (CAS 100-01-6)
- N-(3-Amino-2-methylphenyl)-4-butoxybenzamide (CAS 1017024-98-4)
- 1-(Cyclohexylamino)-4-((4-ethoxyphenyl)amino)anthracene-9,10-dione (CAS 77946-99-7)
- Diethyl bis(2-fluorobenzyl)malonate (CAS 91319-43-6)
- Methyl 2-(2,5-difluorophenyl)propanoate (CAS 1339462-54-2)
- 4’,5’-Dimethoxy-2’-nitroacetophenone (CAS 4101-32-0)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
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