Palbociclib Impurity 136 CAS CATO-C4X-1125136
| CAS No. | CATO-C4X-1125136 |
| Molecular Formula | C26H29N7O4 |
| Molecular Weight | 503.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Palbociclib Impurity 136 (CAS CATO-C4X-1125136) is a certified pharmaceutical impurity reference standard with the molecular formula C26H29N7O4 and a molecular weight of 503.55 g/mol.
Palbociclib Impurity 136 (C26H29N7O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Palbociclib Impurity 136 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H29N7O4 |
| Molecular Weight | 503.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
Related Palbociclib Standards
- Palbociclib Impurity 103 (CAS 2270982-31-3)
- Palbociclib Impurity 79 (CAS CATO-C4X-112579)
- Palbociclib Impurity 85 (CAS CATO-C4X-112585)
- Palbociclib Impurity 198 (CAS CATO-C4X-1125198)
- Palbociclib impurity 129 (CAS CATO-C4X-1125129)
- Palbociclib Impurity 18 (CAS 571189-65-6)
- Palbociclib Impurity 167 (CAS CATO-C4X-1125167)
- Palbociclib Impurity 101 (CAS CATO-C4X-1125101)
Recommended Standards
- Benidipine Impurity 68 (CAS CATO-C4X-112068)
- Ceftazidime Impurity 107 (CAS CATO-C4X-1212107)
- Dehydro Benidipine (CAS 118935-44-7)
- Ceftazidime Impurity 93 (CAS CATO-C4X-121293)
- Resmetirom impurity 129 (CAS CATO-C4X-2912129)
- Tulathromycin A Impurity 1 (CAS CATO-C4X-21071)
- Istradefylline impurity 34 (CAS CATO-C4X-106134)
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- (1-((2-Bromocyclohexyl)oxy)ethyl)benzene (CAS 1247640-30-7)
- 4-(Cycloheptylmethyl)piperidine hydrochloride (CAS 188844-26-0)
- (5E)-5-Benzylidene-2-mercapto-3-phenyl-3,5-dihydro-4H-imidazol-4-one (CAS 145693-86-3)
- N-Cycloheptyl-5-isopropyl-2-methoxybenzenesulfonamide (CAS 946378-63-8)
- 2-(2,5-dimethyl-7-oxo-pyrazolo[1,5-a]pyrimidin-4-yl)acetic acid (CAS 1007215-68-0)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
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