Dapagliflozin Impurity 121 CAS CATO-C4X-1138121
| CAS No. | CATO-C4X-1138121 |
| Molecular Formula | C15H14BrClO |
| Molecular Weight | 325.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dapagliflozin Impurity 121.
CATO supplies Dapagliflozin Impurity 121 (CAS CATO-C4X-1138121), a pharmacopoeial impurity reference standard (molecular formula C15H14BrClO, MW 325.63 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Dapagliflozin Impurity 121 (C15H14BrClO) is characterized by a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dapagliflozin Impurity 121 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14BrClO |
| Molecular Weight | 325.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 10 (CAS 461432-23-5)
- Dapagliflozin Impurity 122 (CAS CATO-C4X-1138122)
- Dapagliflozin Impurity 123 (CAS CATO-C4X-1138123)
- Dapagliflozin Impurity 141 (CAS 1629862-21-0)
- Dapagliflozin Impurity 142 (CAS CATO-C4X-1138142)
- Dapagliflozin Impurity 151 (CAS CATO-C4X-1138151)
- Dapagliflozin Impurity 183 (CAS CATO-C4X-1138183)
- Dapagliflozin Impurity 198 (CAS 2454263-77-3)
Recommended Standards
- Canagliflozin Impurity 15 (CAS 1830346-16-1)
- p-Bromobenzhydryl 2-Chloroethyl Ether (CAS 71783-98-7)
- 5-Bromo-3-methylbenzo[b]thiophene-2-sulphonyl chloride (CAS 338797-11-8)
- (3-Bromophenyl)(4-chloro-3,5-dimethylphenyl)methanol (CAS 1443351-75-4)
- Cefodizime Impurity 2 (CAS CATO-C4X-18062)
- Ziprasidone EP Impurity A HCl (CAS 87691-88-1)
- Bempedoic Acid Impurity 6 (CAS 3023294-04-1)
- 6-bromo-4-cyclopentyl-7-fluoro-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 1712902-48-1)
- 3-Cyano-5-isoxazolecarboxylic acid (CAS 251912-76-2)
- 1,3-Benzenedicarboxylic acid, polymer with 1,6-hexanediamine and hexanedioic acid (CAS 26353-66-2)
- 3-Bromo-4-propoxybenzylamine (CAS 1310248-08-8)
- tert-Butyl 2-[(4R,6S)-2,2-Dimethyl-6-[(1-phenyl-1H-terazol-5-ylsulfonyl)methyl]-1,3-dioxan-4-yl]acetate (CAS 380460-37-7)
- N,N-Dibutyl-2-((3-(trichloromethyl)-1,2,4-thiadiazol-5-yl)oxy)acetamide (CAS 89781-33-9)
- Tau Peptide (401-411)-Lys-Lys trifluoroacetate salt (CAS 2022956-59-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com