Dapagliflozin Impurity 141 CAS 1629862-21-0
| CAS No. | 1629862-21-0 |
| Molecular Formula | C15H14BrClO |
| Molecular Weight | 325.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Dapagliflozin Impurity 141 (CAS 1629862-21-0, C15H14BrClO) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system, Dapagliflozin Impurity 141 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Dapagliflozin Impurity 141 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H14BrClO |
| Molecular Weight | 325.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl/Br-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 10 (CAS 461432-23-5)
- Dapagliflozin Impurity 121 (CAS CATO-C4X-1138121)
- Dapagliflozin Impurity 122 (CAS CATO-C4X-1138122)
- Dapagliflozin Impurity 123 (CAS CATO-C4X-1138123)
- Dapagliflozin Impurity 142 (CAS CATO-C4X-1138142)
- Dapagliflozin Impurity 151 (CAS CATO-C4X-1138151)
- Dapagliflozin Impurity 183 (CAS CATO-C4X-1138183)
- Dapagliflozin Impurity 198 (CAS 2454263-77-3)
Recommended Standards
- Canagliflozin Impurity 15 (CAS 1830346-16-1)
- Dapagliflozin Impurity 87 (CAS CATO-C4X-113887)
- p-Bromobenzhydryl 2-Chloroethyl Ether (CAS 71783-98-7)
- Dapagliflozin Impurity 88 (CAS CATO-C4X-113888)
- Epinephrine /Adrenaline Impurity 56 (CAS 25015-92-3)
- Dopamine Impurity 109 (CAS CATO-C4X-1908109)
- Erythromycin impurity 75 (CAS 15797-36-1)
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- Metoclopramide Impurity 84 (CAS 2486-67-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com