Dapagliflozin Impurity 10 CAS 461432-23-5
| CAS No. | 461432-23-5 |
| Molecular Formula | C15H14BrClO |
| Molecular Weight | 325.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Dapagliflozin Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Dapagliflozin Impurity 10 (CAS 461432-23-5), a pharmacopoeial impurity reference standard (molecular formula C15H14BrClO, MW 325.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Dapagliflozin Impurity 10 (C15H14BrClO) contains a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 325.63 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H14BrClO |
| Molecular Weight | 325.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 121 (CAS CATO-C4X-1138121)
- Dapagliflozin Impurity 122 (CAS CATO-C4X-1138122)
- Dapagliflozin Impurity 123 (CAS CATO-C4X-1138123)
- Dapagliflozin Impurity 141 (CAS 1629862-21-0)
- Dapagliflozin Impurity 142 (CAS CATO-C4X-1138142)
- Dapagliflozin Impurity 151 (CAS CATO-C4X-1138151)
- Dapagliflozin Impurity 183 (CAS CATO-C4X-1138183)
- Dapagliflozin Impurity 198 (CAS 2454263-77-3)
Recommended Standards
- Canagliflozin Impurity 15 (CAS 1830346-16-1)
- p-Bromobenzhydryl 2-Chloroethyl Ether (CAS 71783-98-7)
- 5-Bromo-3-methylbenzo[b]thiophene-2-sulphonyl chloride (CAS 338797-11-8)
- (3-Bromophenyl)(4-chloro-3,5-dimethylphenyl)methanol (CAS 1443351-75-4)
- Cyclophosphamide Impurity 1 HCl (CAS CATO-C4X-23061)
- Semaglutide impurity 268 (CAS CATO-C4X-2226268)
- Carvedilol Impurity 26 (CAS 2248746-67-8)
- 4-Bromobicyclo[2.1.1]Hexan-1-ol (CAS 2387596-39-4)
- tert-Butyl cis-N-(4-amino-1-methyl-cyclohexyl)carbamate hydrochloride (CAS 2227199-12-2)
- methyl 1-(2-ethoxy-2-oxoethyl)-6-(2-furyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-34-7)
- 2-Azetidinomethyl-4-fluorobenzophenone (CAS 898754-83-1)
- 2-Bromo-4H,5H,6H,7H-thieno[2,3-c]pyridine hydrobromide (CAS 1423033-44-6)
- 2-Boc-5-hydroxy-2-azabicyclo[2.2.1]heptane (CAS 207405-60-5)
- D-Glu3-Tirzepatide (CAS CATO-CPTD788927)
Why CATO?
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