Dapagliflozin Impurity 160 CAS CATO-C4X-1138160
| CAS No. | CATO-C4X-1138160 |
| Molecular Formula | C23H27ClO7 |
| Molecular Weight | 450.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Dapagliflozin Impurity 160 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Dapagliflozin Impurity 160 (CAS CATO-C4X-1138160, C23H27ClO7) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C23H27ClO7, Dapagliflozin Impurity 160 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 450.91 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Dapagliflozin Impurity 160 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27ClO7 |
| Molecular Weight | 450.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Dapagliflozin Standards
- Dapagliflozin Impurity 149 (CAS 1616259-14-3)
- Dapagliflozin Impurity 159 (CAS CATO-C4X-1138159)
- Dapagliflozin Impurity 191 (CAS 1616259-44-9)
- Dapagliflozin Impurity 4 (CAS 1632287-34-3)
- Dapagliflozin Impurity 117 (CAS 2377899-45-9)
- Dapagliflozin Impurity 135 (CAS CATO-C4X-1138135)
- Dapagliflozin 4-Bromo Analog (CAS 1807632-95-6)
- Dapagliflozin Impurity 118 (CAS CATO-C4X-1138118)
Recommended Standards
- Empagliflozin Impurity 6 (CAS CATO-C4X-10656)
- Ethyl 1-(4-chlorophenyl)-4-((4-methoxybenzyl)amino)-3-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 866133-73-5)
- Empagliflozin Impurity 53 (CAS CATO-C4X-106553)
- 496794-70-8 N-(4-chloro-3-(6-(dimethylamino)-1H-benzo[d]imidazol-2-yl)phenyl)-3,5-dimethoxybenzamide Stemolecule SMO Antagonist (CAS 496794-70-8)
- Etoposide EP Impurity B (CAS 100007-56-5)
- Estriol Impurity 26 (CAS CATO-C4X-163726)
- Ilaprazole Impurity 78 (CAS CATO-C4X-113078)
- Methyl 2-ethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 851334-98-0)
- 1-(6-(Tritylamino)pyridin-3-yl)ethan-1-one (CAS 49647-11-2)
- (R)-1-(3-(Difluoromethyl)-2-fluorophenyl)ethan-1-amine hydrochloride (CAS 2569698-42-4)
- ((2S,3S)-3-(2-(3,3-dimethylaziridin-2-yl)ethyl)-3-methyloxiran-2-yl)methanol (CAS 1534354-56-7)
- 3,3-Difluoro-3-(4-fluorophenyl)-2-hydroxypropionic acid (CAS 541508-26-3)
- 3-(4-(Trifluoromethyl)benzyl)dihydro-2H-pyran-4(3H)-one (CAS 1956325-33-9)
- D-Asp15-Tirzepatide (CAS CATO-CPTD788919)
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