Lenvatinib Impurity 125 CAS CATO-C4X-1140125
| CAS No. | CATO-C4X-1140125 |
| Molecular Formula | C27H22Cl2N4O5 |
| Molecular Weight | 553.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Lenvatinib Impurity 125 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Lenvatinib Impurity 125 (CAS CATO-C4X-1140125, C27H22Cl2N4O5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lenvatinib Impurity 125 (C27H22Cl2N4O5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C27H22Cl2N4O5 |
| Molecular Weight | 553.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Lenvatinib Standards
- Lenvatinib Impurity 123 (CAS CATO-C4X-1140123)
- Lenvatinib Impurity 126 (CAS CATO-C4X-1140126)
- Lenvatinib Impurity 58 (CAS CATO-C4X-114058)
- Lenvatinib Impurity 67 (CAS 2380197-90-8)
- Lenvatinib Impurity 181 (CAS CATO-C4X-1140181)
- Lenvatinib Impurity 182 (CAS CATO-C4X-1140182)
- Lenvatinib Impurity 88 (CAS CATO-C4X-114088)
- Lenvatinib Impurity 145 (CAS CATO-C4X-1140145)
Recommended Standards
- 4,7-Bis(5-bromo-2-thienyl)-2-n-octyl-2H-benzotriazole (CAS 1254062-41-3)
- (E)-{[2-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)phenyl]methylidene}[(4-chlorophenyl)methoxy]amine (CAS 338409-03-3)
- 4,7-Bis(5-bromothiophen-2-yl)-2-octyl-2H-benzo[d][1,2,3]triazole (CAS 1254062-39-9)
- (E)-4-((3,4-dichlorobenzyl)oxy)-N'-(4-((4-fluorobenzyl)oxy)-3-methoxybenzylidene)benzohydrazide (CAS 320423-56-1)
- Upadacitinib Impurity 38 (CAS CATO-C4X-240538)
- Arotinolol Impurity 76 (CAS CATO-C4X-185476)
- Somatostatin Impurity 9 (CAS CATO-C4X-23509)
- 4-(2-thiazol-5-ylethynyl)-1,2-benzoxazol-3-amine (CAS 2526799-34-6)
- Lifitegrast Impurity 3 (CAS CATO-C4X-24093)
- Alanyl Glutamine Impurity 44 TFA Salt (CAS CATO-C4X-197444)
- 3-((1,3-Dioxoisoindolin-2-yl)methyl)benzonitrile (CAS 62898-68-4)
- Methyl 2-bromo-8-hydroxyindolizine-7-carboxylate (CAS 1706444-83-8)
- 1-Methyl-1-octylpyrrolidin-1-ium chloride (CAS 909398-60-3)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com