Avatrombopag impurity 134 CAS CATO-C4X-2234134
| CAS No. | CATO-C4X-2234134 |
| Molecular Formula | C7H4BrClN2S2 |
| Molecular Weight | 295.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C7H4BrClN2S2, Avatrombopag impurity 134 contains a nitrile group, sulfur-containing functionality, chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 295.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Avatrombopag impurity 134 (CAS CATO-C4X-2234134) is a certified pharmaceutical impurity reference standard with the molecular formula C7H4BrClN2S2 and a molecular weight of 295.61 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4BrClN2S2 |
| Molecular Weight | 295.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 24 (CAS 1534575-19-3)
- Avatrombopag Impurity 38 (CAS 2161380-87-4)
- Avatrombopag Impurity 43 (CAS 1268118-96-2)
- Avatrombopag Impurity 144 (CAS CATO-C4X-2234144)
- Avatrombopag impurity 125 (CAS CATO-C4X-2234125)
- Avatrombopag Impurity 18 (CAS 958457-83-5)
- Avatrombopag Impurity 72 (CAS CATO-C4X-223472)
- Avatrombopag Impurity 50 (CAS CATO-C4X-223450)
Recommended Standards
- N-(2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)ethanamine (CAS 2096333-72-9)
- 5-Bromo-4-chloro-2-(methylthio)thieno[2,3-d]pyrimidine (CAS 1823552-34-6)
- 3-Chloro-2-((difluoromethyl)sulfonyl)-5-(trifluoromethyl)pyridine (CAS 1823183-18-1)
- 2-(Difluoromethyl)-4-(trifluoromethyl)pyridine-5-sulfonyl chloride (CAS 1806810-68-3)
- Sitafloxacin Impurity 36 (CAS CATO-C4X-115536)
- Carfilzomib Impurity 92 (CAS CATO-C4X-102292)
- Milnacipran Impurity 13 (CAS 19532-98-0)
- (Z)-SABINENE HYDRATE (CAS 15537-55-0)
- 1-(3-Chloropyrazin-2-yl)piperidine-4-carboxylic acid (CAS 1543014-69-2)
- 2-(3-(Tert-butyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-2-yl)ethan-1-amine (CAS 1784217-07-7)
- 5453-80-5 Bicyclo(2.2.1)hept-5-ene-2-carbaldehyde Bicyclo(2.2.1)hept-5-ene-2-carboxaldehyde AI3-10023 EINECS 226-698-9 5-Norbornene-2-carboxaldehyde NSC 18897 (CAS 5453-80-5)
- 2-Methylaminomethylphenylamine, 97% (CAS 1904-69-4)
- 2-(3-Nitro-1h-pyrazol-1-yl)acetamide (CAS 1003011-27-5)
- Hexapeptide-10 (CAS 146439-94-3)
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