Lenvatinib Impurity 41 CAS CATO-C4X-114041
| CAS No. | CATO-C4X-114041 |
| Molecular Formula | C20H14ClNO5 |
| Molecular Weight | 383.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Lenvatinib Impurity 41 (CAS CATO-C4X-114041, C20H14ClNO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Lenvatinib Impurity 41 (C20H14ClNO5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 383.78 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H14ClNO5 |
| Molecular Weight | 383.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lenvatinib Standards
- Lenvatinib Impurity 173 (CAS CATO-C4X-1140173)
- Lenvatinib Impurity 3 (CAS 417719-51-8)
- Lenvatinib Impurity 42 (CAS 2733083-03-7)
- Lenvatinib Impurity 87 (CAS CATO-C4X-114087)
- Lenvatinib Impurity 1 (CAS 417714-14-8)
- Lenvatinib Impurity 4 (CAS 417719-45-0)
- Lenvatinib Impurity 172 (CAS CATO-C4X-1140172)
- Lenvatinib Impurity 162 (CAS CATO-C4X-1140162)
Recommended Standards
- N3-[5-phenyl-4-(trifluoromethyl)-1,3-thiazol-2-yl]-2-chloronicotinamide (CAS 256414-68-3)
- 2,3,4-Tribromo-6-(trifluoromethyl)pyridine (CAS 1214383-04-6)
- N-(5-(2-Chlorophenyl)-1,3,4-thiadiazol-2-yl)-2-(trifluoromethyl)benzamide (CAS 391863-61-9)
- 7-Chloro-2-(4-methoxy-2-methylphenyl)-2,3-dihydropyridazino[4,5-b]quinoline-1,4,10(5H)-trione (CAS 170142-20-8)
- Entacapone Impurity 5（Mixture of chiral isomers） (CAS CATO-C4X-16295)
- Palbociclib Impurity 177 (CAS CATO-C4X-1125177)
- Empagliflozin Impurity 240 (CAS CATO-C4X-1065240)
- H-Ser(tBu)-OBzl.HCl (CAS 1401668-21-0)
- 3-Fluoro-4-(trifluoromethoxy)benzamide (CAS 886499-18-9)
- n-Methoxy-n,5-dimethylpyrazine-2-carboxamide (CAS 317335-27-6)
- 2-(4-Aminobicyclo[2.2.2]octan-1-yl)acetonitrile hydrochloride (CAS 2230691-53-7)
- (S)-2-(4'-Methoxy-[1,1'-biphenyl]-4-ylsulfonamido)-3-methylbutanoic acid (CAS 199850-81-2)
- 1-chloro-4-fluoro-5-iodo-2-methylbenzene (CAS 1263275-80-4)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
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