Adefovir Impurity 28 CAS CATO-C4X-115228
| CAS No. | CATO-C4X-115228 |
| Molecular Formula | C20H32N5O8P |
| Molecular Weight | 501.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 501.47 g/mol gives Adefovir Impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Adefovir Impurity 28 (CAS CATO-C4X-115228) is a certified pharmaceutical impurity reference standard with the molecular formula C20H32N5O8P and a molecular weight of 501.47 g/mol.
Adefovir Impurity 28 (C20H32N5O8P) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H32N5O8P |
| Molecular Weight | 501.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Adefovir Standards
- Adefovir Dipivoxil (CAS 142340-99-6)
- Adefovir Impurity 30 (CAS 365417-53-4)
- Adefovir impurity 38 (CAS CATO-C4X-115238)
- Adefovir Impurity 8 (CAS 1416439-02-5)
- Adefovir Impurity 15 (CAS CATO-C4X-115215)
- Adefovir Impurity 29 (CAS CATO-C4X-115229)
- Adefovir impurity 11 (CAS CATO-C4X-115211)
- Adefovir Impurity 16 (CAS CATO-C4X-115216)
Recommended Standards
- 16-Nitroanthra[9,1,2-cde]benzo[rst]pentaphene-5,10-dione (CAS 128-60-9)
- Lifitegrast Impurity 43 (CAS CATO-C4X-240943)
- N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-((4-methoxytetrahydro-2H-pyran-4-yl)oxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)benzamide (CAS 60943-92-2)
- Calcium Folinate EP Impurity B (Mixture of Diastereomers) (CAS 98814-60-9)
- Chlortetracycline EP Impurity H (CAS 7301-38-4)
- Tinidazole Impurity 13 (CAS CATO-C4X-193013)
- Prednisolone Impurity 22 (CAS 37927-29-0)
- Benzoylnorecgonine (CAS 41889-45-6)
- 4-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]-1,2,5-oxadiazol-3-amine (CAS 329212-59-1)
- 2-(3-Hydroxypiperidin-1-yl)-1-phenylethan-1-one (CAS 1248914-71-7)
- BCN-PEG3-Biotin (CAS 1263166-92-2)
- 7-Chloropyrazolo[1,5-α]pyrimidine (CAS 58347-49-2)
- 2-(Benzo[d]thiazol-2-yl)-4-methyloxazole (CAS 93472-34-5)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
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