Lifitegrast Impurity 43 CAS CATO-C4X-240943
| CAS No. | CATO-C4X-240943 |
| Molecular Formula | C23H34Cl2N4O4 |
| Molecular Weight | 501.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Lifitegrast Impurity 43 (CAS CATO-C4X-240943), a pharmacopoeial impurity reference standard (molecular formula C23H34Cl2N4O4, MW 501.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Lifitegrast Impurity 43 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 501.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Lifitegrast Impurity 43 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H34Cl2N4O4 |
| Molecular Weight | 501.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Lifitegrast Standards
- Lifitegrast Impurity 60 (CAS CATO-C4X-240960)
- Lifitegrast Impurity 68 (CAS CATO-C4X-240968)
- Lifitegrast Impurity 131 (CAS CATO-C4X-2409131)
- Lifitegrast Impurity 115 (CAS CATO-C4X-2409115)
- Lifitegrast Impurity 75 (CAS CATO-C4X-240975)
- Lifitegrast Impurity 54 (CAS CATO-C4X-240954)
- Lifitegrast Impurity 37 (CAS 1194550-56-5)
- Lifitegrast Impurity 170 (CAS CATO-C4X-2409170)
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- N,N'-(Sulfonylbis(4,1-phenylene))bis(2-(dicyclohexylamino)acetamide) (CAS 2907-88-2)
- Dotinurad Impurity 187 (CAS CATO-C4X-2494187)
- 2,6-Dibromo-3,5-dichloro-4-fluoroaniline (CAS 1160573-76-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com