Bedaquiline Impurity 27 CAS CATO-C4X-116727

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-116727
Molecular FormulaC30H27BrN2O2
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bedaquiline Impurity 27 CAS CATO-C4X-116727 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bedaquiline Impurity 27.

CATO supplies Bedaquiline Impurity 27 (CAS CATO-C4X-116727), a pharmacopoeial impurity reference standard (molecular formula C30H27BrN2O2C2HF3O2, MW 641.48 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, Bedaquiline Impurity 27 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 641.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Bedaquiline Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC30H27BrN2O2 C2HF3O2
Molecular Weight641.48 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)18.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF/Br-containing
Nitrogen Atoms2

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