Fosaprepitant Impurity 49（Racemate） CAS CATO-C4X-116849
| CAS No. | CATO-C4X-116849 |
| Molecular Formula | C21H19F6NO3 |
| Molecular Weight | 447.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fosaprepitant Impurity 49（Racemate）.
CATO supplies Fosaprepitant Impurity 49（Racemate） (CAS CATO-C4X-116849), a pharmacopoeial impurity reference standard (molecular formula C21H19F6NO3, MW 447.37 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C21H19F6NO3, Fosaprepitant Impurity 49（Racemate） contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 447.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fosaprepitant Impurity 49（Racemate） meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H19F6NO3 |
| Molecular Weight | 447.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fosaprepitant Standards
- Fosaprepitant Impurity 16 (CAS 327623-34-7)
- Fosaprepitant Impurity 59 (CAS CATO-C4X-116859)
- Fosaprepitant Impurity 30 (CAS 327623-37-0)
- Fosaprepitant Impurity 37 (CAS CATO-C4X-116837)
- Fosaprepitant Impurity 48 (CAS 1707-92-2)
- Fosaprepitant Impurity 53 (CAS 1254261-32-9)
- Fosaprepitant Impurity 38 (CAS 990-91-0)
- Fosaprepitant Impurity 7 (CAS CATO-C4X-11687)
Recommended Standards
- Aprepitant Impurity 78 (CAS CATO-C4X-114178)
- Flecainide-D4 N-nitroso (CAS 2901085-00-3)
- Aprepitant Impurity 77 (CAS CATO-C4X-114177)
- BPA Impurity 4 (CAS CATO-C4X-31394)
- Biapenem Impurity 23 (CAS CATO-C4X-227323)
- Peficitinib Impurity 4 (CAS 944118-26-7)
- Atogepant Impurity 28 (CAS 957122-46-2)
- N-Octadecyl-L-aspartic acid (CAS 70021-38-4)
- tert-Butyl 2-(piperidin-4-ylmethoxy)acetate (CAS 2505504-71-0)
- 1,4-Bis(pyridin-2-ylmethyl)piperazine (CAS 6584-58-3)
- 5-(4-Fluorophenyl)-2-(propan-2-yl)-2,3-dihydro-1h-pyrazol-3-one (CAS 1221725-83-2)
- 3-Bromo-N-(1-cyclopropylethyl)aniline (CAS 1021042-12-5)
- 3-Bromo-6-fluoropyridine-2-carbaldehyde (CAS 1227603-17-9)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com