Fosaprepitant Impurity 37 CAS CATO-C4X-116837
| CAS No. | CATO-C4X-116837 |
| Molecular Formula | C27H37N2O4P |
| Molecular Weight | 484.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Fosaprepitant Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Fosaprepitant Impurity 37 (CAS CATO-C4X-116837, C27H37N2O4P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Fosaprepitant Impurity 37 (C27H37N2O4P) contains a steroid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.5, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 484.57 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C27H37N2O4P |
| Molecular Weight | 484.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Fosaprepitant Standards
- Fosaprepitant Impurity 16 (CAS 327623-34-7)
- Fosaprepitant Impurity 49（Racemate） (CAS CATO-C4X-116849)
- Fosaprepitant Impurity 59 (CAS CATO-C4X-116859)
- Fosaprepitant Impurity 53 (CAS 1254261-32-9)
- Fosaprepitant Impurity 30 (CAS 327623-37-0)
- Fosaprepitant Impurity 38 (CAS 990-91-0)
- Fosaprepitant Impurity 7 (CAS CATO-C4X-11687)
- Fosaprepitant Impurity 48 (CAS 1707-92-2)
Recommended Standards
- Glimepiride EP Impurity H (CAS CATO-C4X-11028)
- Ceftibuten Impurity 13 (CAS 36923-19-0)
- N-methyl-N-(2-(4-(1-(naphthalen-1-ylsulfonyl)-1H-pyrazol-3-yl)phenoxy)ethyl)pyridin-2-amine (CAS 955976-53-1)
- (3,3-Dimethoxy-1-{[(4-methylbenzenesulfonyl)oxy]methyl}cyclobutyl)methyl 4-methylbenzene-1-sulfonate (CAS 1023815-74-8)
- Apalutamide Impurity 15 (CAS 915087-26-2)
- Etrasimod impurity 17 (CAS CATO-C4X-321417)
- Fosfomycin Impurity 19 (CAS 28423-96-3)
- Barium (2S,3R,4S,5S,6R)-4,5-dihydroxy-6-((phosphonooxy)methyl)tetrahydro-2H-pyran-2,3-bis(olate) hydrate(1:1:x) (CAS 150400-00-3)
- 4-(((1r,4r)-4-Aminocyclohexyl)oxy)-2-chlorobenzonitrile hydrochloride (CAS 1335049-54-1)
- 6-bromo-3-methylimidazo[1,2-a]pyridine (CAS 1216222-91-1)
- N-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-2-chloro-N-(3,5-dimethylphenyl)acetamide (CAS 727696-08-4)
- Butyl 5-bromo-2-chlorobenzamide (CAS 1184623-42-4)
- 2-Chloro-N'-[6-chloro-4-(trifluoromethyl)pyridin-2-yl]benzohydrazide (CAS 1797764-46-5)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com