Macitentan Impurity 20 CAS CATO-C4X-117520
| CAS No. | CATO-C4X-117520 |
| Molecular Formula | C15H19BrN4O3S |
| Molecular Weight | 415.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 415.31 g/mol gives Macitentan Impurity 20 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Macitentan Impurity 20 (CAS CATO-C4X-117520), a pharmacopoeial impurity reference standard (molecular formula C15H19BrN4O3S, MW 415.31 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Macitentan Impurity 20 (C15H19BrN4O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 415.31 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Macitentan Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H19BrN4O3S |
| Molecular Weight | 415.31 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Macitentan Standards
- Macitentan Impurity 6 (CAS CATO-C4X-11756)
- Macitentan Impurity 12 (CAS 2300968-85-6)
- Macitentan Impurity 25 (CAS 1393813-43-8)
- Macitentan Impurity 40 (CAS CATO-C4X-117540)
- Macitentan impurity 30 (CAS CATO-C4X-117530)
- Macitentan Impurity 22 (CAS 441797-83-7)
- Macitentan Impurity 44 (CAS CATO-C4X-117544)
- Macitentan Impurity 4 (CAS 2365406-85-3)
Recommended Standards
- tert-Butyl (5-ethyl-1-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)carbamate (CAS 2916870-79-4)
- 7-TFA-ap-7-Deaza-dG (CAS 666847-77-4)
- 4-(tert-Butyl)-N'-((5-(3,4-dichlorophenyl)furan-2-yl)methylene)benzohydrazide (CAS 328922-22-1)
- (S)-2-(3,5-bis(trifluoromethyl)benzyl)-3-((tert-butoxycarbonyl)amino)propanoic acid (CAS 1260590-43-9)
- Tiamulin impurity 12 (CAS CATO-C4X-221012)
- Tobramycin Impurity N2 (CAS 111170-72-0)
- Altrenogest impurity 17 (CAS 32259-88-4)
- 2-(2-Chlorophenyl)azepane (CAS 887360-60-3)
- 4-Methoxythiazole (CAS 69096-72-6)
- (2S,3R,4E)-2-Amino-3-hydroxy-tetradecenoic Acid Ethyl Ester (CAS 1356010-95-1)
- 6-bromo-7-chloro-3H-imidazo[4,5-b]pyridine (CAS 83472-62-2)
- 1,2-Phenylene diisothiocyanate (CAS 71105-17-4)
- N-(4-fluorophenyl)azetidin-3-amine (CAS 920511-30-4)
- Hexapeptide-9 (CAS 885024-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com