Macitentan Impurity 28 CAS CATO-C4X-117528
| CAS No. | CATO-C4X-117528 |
| Molecular Formula | C3H9N3O3S |
| Molecular Weight | 167.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 167.19 g/mol gives Macitentan Impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Macitentan Impurity 28 (CAS CATO-C4X-117528) is a certified pharmaceutical impurity reference standard with the molecular formula C3H9N3O3S and a molecular weight of 167.19 g/mol.
Structurally, Macitentan Impurity 28 (C3H9N3O3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 167.19 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Macitentan Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C3H9N3O3S |
| Molecular Weight | 167.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 1.0 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Macitentan Standards
- Macitentan Impurity 49 (CAS CATO-C4X-117549)
- Macitentan Impurity 8 (CAS 38353-06-9)
- Macitentan Impurity 28 (CAS 147000-89-3)
- Macitentan Impurity 19 (CAS 36082-50-5)
- Macitentan Impurity 37 (CAS CATO-C4X-117537)
- Macitentan Impurity 11 (CAS 1393813-40-5)
- Macitentan Impurity 13 (CAS 3974-18-3)
- Macitentan impurity 51 (CAS CATO-C4X-117551)
Recommended Standards
- Tofacitinib Impurity 206 (CAS CATO-C4X-1079206)
- Famotidine Impurity 81 (CAS CATO-C4X-139281)
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- Azathioprine Impurity 6 (CAS 154-42-7)
- Eravacycline Impurity 4(TP-4308） (CAS CATO-C4X-29384)
- Posaconazole Impurity 77 (CAS 74853-08-0)
- Janagliflozin impurity 7 (CAS CATO-C4X-30327)
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- 2-{1-Azatricyclo[6.3.1.0⁴,¹²]dodeca-2,4,6,8(12)-tetraen-3-yl}acetic acid (CAS 149542-66-5)
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- 2’,5’-Dimethyl-2’H-[1,3’-bipyrazole]-4’-carboxylic Acid (CAS 1152565-59-7)
- 2-(2-Bromoallyl)isoindoline-1,3-dione (CAS 500589-29-7)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com