Macitentan Impurity 56 CAS CATO-C4X-117556
| CAS No. | CATO-C4X-117556 |
| Molecular Formula | C19H19Br2N5O2 |
| Molecular Weight | 509.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Macitentan Impurity 56 (CAS CATO-C4X-117556) is a certified pharmaceutical impurity reference standard with the molecular formula C19H19Br2N5O2 and a molecular weight of 509.19 g/mol.
The molecular framework of Macitentan Impurity 56 (C19H19Br2N5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Macitentan Impurity 56 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H19Br2N5O2 |
| Molecular Weight | 509.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 5 |
Related Macitentan Standards
- Macitentan Impurity 16 (CAS 2211059-00-4)
- Macitentan Impurity 21 (CAS CATO-C4X-117521)
- Macitentan Impurity 57 (CAS CATO-C4X-117557)
- Macitentan Impurity 55 (CAS CATO-C4X-117555)
- Macitentan Impurity 33 (CAS 1642873-05-9)
- Macitentan Impurity N1 (CAS 2443747-63-3)
- Macitentan Impurity 35 (CAS 441798-36-3)
- Macitentan Impurity 8 (CAS 556796-88-4)
Recommended Standards
- 5'-Adenylic acid, anhydride with P,P'-(difluoromethylene)bis[phosphonic acid] (CAS 81336-78-9)
- N-((2,5-Dichloro-4-((1,1,2,2-tetrafluoroethyl)sulfonyl)phenyl)carbamoyl)-2,6-difluorobenzamide (CAS 100341-28-4)
- 2-(Furan-2-yl)-5-phenyl-1,3,4-oxadiazole (CAS 14093-97-1)
- N-((2,3-Dichloro-4-((1,1,2,2-tetrafluoroethyl)sulfonyl)phenyl)carbamoyl)-2,6-difluorobenzamide (CAS 100341-30-8)
- Etomidate Impurity 22 (CAS CATO-C4X-188422)
- Iobitridol Impurity 26 (CAS CATO-C4X-317826)
- Tedizolid Impurity 84 (CAS CATO-C4X-105484)
- Fluorescein mono-β-D-galactopyranoside (CAS 102286-67-9)
- 1-Methyl-4-(2-piperidin-2-yl-ethyl)-piperazine (CAS 856843-58-8)
- 5-Cyclopropyl-1,2,4-oxadiazole-3-carboxylic acid (CAS 1339872-07-9)
- N-(2-(Dimethylamino)ethyl)quinoline-8-sulfonamide (CAS 158729-31-8)
- LL-37 amide trifluoroacetate salt (CAS 597562-32-8)
- Neogambogic Acid (CAS 93772-31-7)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com