Hydrochlorothiazide Impurity 54 CAS CATO-C4X-117754
| CAS No. | CATO-C4X-117754 |
| Molecular Formula | C6H5Cl2NO2S |
| Molecular Weight | 226.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Hydrochlorothiazide Impurity 54 (CAS CATO-C4X-117754), a certified reference material (molecular formula C6H5Cl2NO2S, MW 226.08 g/mol) for analytical method development and quality control.
The molecular framework of Hydrochlorothiazide Impurity 54 (C6H5Cl2NO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5Cl2NO2S |
| Molecular Weight | 226.08 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Hydrochlorothiazide Standards
- Hydrochlorothiazide Impurity 57 (CAS CATO-C4X-117757)
- Hydrochlorothiazide Impurity 35 (CAS CATO-C4X-117735)
- Hydrochlorothiazide Impurity 36 (CAS CATO-C4X-117736)
- Hydrochlorothiazide Impurity 23 (CAS 19477-32-8)
- Hydrochlorothiazide Impurity 29 (CAS 957785-35-2)
- Hydrochlorothiazide Impurity 1 (CAS 133-74-4)
- Hydrochlorothiazide Impurity 40 (CAS CATO-C4X-117740)
- Hydrochlorothiazide Impurity 41 (CAS CATO-C4X-117741)
Recommended Standards
- N,N-Dichlorobenzenesulfonamide (CAS 473-29-0)
- Ethyl 4,5-dichlorothiazole-2-carboxylate (CAS 79807-38-8)
- Diazoxide impurity 9 (CAS CATO-C4X-19529)
- Ethyl 4,5-dichloroisothiazole-3-carboxylate (CAS 296243-98-6)
- (R)-3-Hydroxy-N,N-dimethylpyrrolidine-1-carboxamide (CAS 1315054-87-5)
- Methyl 4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carboxylate (CAS 1227664-25-6)
- 4-Methyl-3-thioxoisoindolin-1-one (CAS 6629-81-8)
- 1,2-Di(naphthalen-2-yl)ethane-1,2-dione (CAS 29574-57-0)
- 2,2′-(1,3-Phenylene)bis[4,5-dihydro-4-(1-methylethyl)oxazole] (CAS 1222086-30-7)
- 2-(4-Bromophenoxy)-N,N-dimethylethylamine-d6 (CAS 1794787-00-0)
- 2-(5,5-Dimethyl-2,4-dioxoimidazolidin-1-yl)acetic acid (CAS 64942-63-8)
- 2-Chloro-1-[(4-methylbenzene)sulfonyl]-1H-indole (CAS 1881331-24-3)
- 1-(5-Chlorothiophene-2-carbonyl)pyrrolidine-2-carboxylic acid (CAS 351493-11-3)
- Polymyxin B nonapeptide (CAS 86408-36-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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