Hydrochlorothiazide Impurity 35 CAS CATO-C4X-117735
| CAS No. | CATO-C4X-117735 |
| Molecular Formula | C7H8ClNO3S |
| Molecular Weight | 221.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Hydrochlorothiazide Impurity 35.
Hydrochlorothiazide Impurity 35 (CAS CATO-C4X-117735) is a certified pharmaceutical impurity reference standard with the molecular formula C7H8ClNO3S and a molecular weight of 221.66 g/mol.
Based on its molecular formula C7H8ClNO3S, Hydrochlorothiazide Impurity 35 contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 221.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Hydrochlorothiazide Impurity 35 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO3S |
| Molecular Weight | 221.66 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Hydrochlorothiazide Standards
- Hydrochlorothiazide Impurity 36 (CAS CATO-C4X-117736)
- Hydrochlorothiazide Impurity 23 (CAS 19477-32-8)
- Hydrochlorothiazide Impurity 54 (CAS CATO-C4X-117754)
- Hydrochlorothiazide Impurity 57 (CAS CATO-C4X-117757)
- Hydrochlorothiazide Impurity 1 (CAS 133-74-4)
- Hydrochlorothiazide Impurity 40 (CAS CATO-C4X-117740)
- Hydrochlorothiazide Impurity 41 (CAS CATO-C4X-117741)
- Hydrochlorothiazide Impurity 29 (CAS 957785-35-2)
Recommended Standards
- 1319AF 2-Chloro-N-(5-methoxymethyl-[1,3,4]thiadiazol-2-yl)-acetamide 876710-55-3 C6H8ClN3O2S (CAS 876710-55-3)
- 6387-22-0 5-Amino-3-chlorotoluene-2-sulphonic acid EINECS 228-992-2 (CAS 6387-22-0)
- Torasemide impurity 33 (CAS CATO-C4X-183633)
- N-(3-Chloro-4-hydroxyphenyl)methanesulfonamide (CAS 321962-11-2)
- Mometasone Furoate Impurity 23 (CAS 83897-05-6)
- Atogepant Impurity 16 (CAS CATO-C4X-328516)
- Abiraterone Impurity N6 (CAS 853-23-6)
- IMMH-010 Impurity 4 (CAS CATO-C4X-28824)
- 1-[4-(2-methylpropyl)phenyl]methanamine (CAS 667906-61-8)
- 2-((5-(((4-Chlorophenyl)amino)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dimethylphenyl)acetamide (CAS 352684-82-3)
- 3-[(Tert-butylcarbamoyl)amino]-4-chlorobenzoic acid (CAS 1042774-68-4)
- 7-Hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-6-carboxylic acid (CAS 1038374-76-3)
- 5-(4-Methoxyphenyl)-4,5-dihydroisoxazol-5-ol (CAS 53009-32-8)
- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com