Eltrombopag Impurity 133 CAS CATO-C4X-1198133
| CAS No. | CATO-C4X-1198133 |
| Molecular Formula | C20H14BrNO5 |
| Molecular Weight | 428.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Eltrombopag Impurity 133.
Eltrombopag Impurity 133 (CAS CATO-C4X-1198133) is a certified pharmaceutical impurity reference standard with the molecular formula C20H14BrNO5 and a molecular weight of 428.23 g/mol.
Structurally, Eltrombopag Impurity 133 (C20H14BrNO5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 428.23 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Eltrombopag Impurity 133 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H14BrNO5 |
| Molecular Weight | 428.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Eltrombopag Standards
- Eltrombopag Impurity 71 (CAS CATO-C4X-119871)
- Eltrombopag impurity 149 (CAS CATO-C4X-1198149)
- Eltrombopag Impurity 106 (CAS CATO-C4X-1198106)
- Eltrombopag Impurity 4 (CAS 1246929-02-1)
- Eltrombopag impurity 147 (CAS CATO-C4X-1198147)
- ELTROMBOPAG (CAS 1807882-48-9)
- Eltrombopag (CAS 496775-61-2)
- (E)-Eltrombopag (CAS CATO-C4X-119872)
Recommended Standards
- N-(4-Cyano-1,3-diphenyl-1H-pyrazol-5-yl)-2-iodoacetamide (CAS 189757-40-2)
- 1-(Benzylsulfonyl)-2-iodo-5-methoxy-1H-pyrrolo[3,2-b]pyridine (CAS 1352397-59-1)
- 5-Bromo-2-(4-fluorophenyl)-6-(methylsulfonamido)benzofuran-3-carboxylic acid (CAS 1333244-32-8)
- 3-Iodo-5-methoxy-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 945256-30-4)
- Cefazolin EP Impurity J (CAS 1675245-00-7)
- Trazodone Impurity 7 (CAS 53818-10-3)
- Cefradine EP Impurity C (CAS CATO-C4X-12157)
- 5-(3-Chloro-4-methylphenyl)oxazole (CAS 1996343-80-6)
- (2Z)-N-(2,4-Dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-enamide (CAS 329779-55-7)
- 1-Methyl-piperazine-2-carboxylic acid dihydrochloride (CAS 1246550-14-0)
- 2-Cyclopentylpropan-2-amine hydrochloride (CAS 1423027-16-0)
- Clenbuterol EP impurity F (CAS 37153-52-9)
- 4-Cyano-3-fluorobenzeneboronic acid pinacol ester, >97% (CAS 870238-67-8)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com