Betamethasone impurity 45 CAS 1215899-29-8
| CAS No. | 1215899-29-8 |
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Betamethasone impurity 45 (CAS 1215899-29-8, C22H30FO8P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Betamethasone impurity 45 (C22H30FO8P) contains a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Betamethasone impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone impurity 103 (CAS CATO-C4X-1437103)
- Betamethasone Impurity 132 (CAS CATO-C4X-1437132)
- Betamethasone Impurity 135 (CAS CATO-C4X-1437135)
- Betamethasone impurity 55 (CAS 1202002-02-5)
- Betamethasone impurity 56 (CAS 1202002-00-3)
- Betamethasone impurity 96 (CAS CATO-C4X-143796)
- Betamethasone Unknown Impurity 3 (CAS CATO-CPS-2303001)
- Betamethasone Acetate EP Impurity C (CAS 330157-05-6)
Recommended Standards
- Dexamethasone impurity 65 (CAS 1202002-01-4)
- Dexamethasone impurity 64 (CAS CATO-C4X-116564)
- 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-4-phenyl-4H-1,2,4-triazole (CAS 344269-64-3)
- Dexamethasone impurity 63 (CAS 1202001-99-7)
- Fulvestrant Impurity 16 (CAS CATO-C4X-191716)
- Cisatracurium EP Impurity M Ditrifluoroacetate (CAS CATO-C4X-185072)
- Cedric acetate impurity 2（TFA） (CAS CATO-CPTD788583)
- (S)-2-Amino-2-(4-bromo-2-chlorophenyl)ethan-1-ol (CAS 1212995-13-5)
- n-(Furan-2-ylmethyl)-1-propylpiperidin-4-amine (CAS 765924-11-6)
- 14378-32-6 Zinc, isotope of mass 64 Zinc-64 (CAS 14378-32-6)
- Sodium phthalimide (CAS 33081-78-6)
- 2-(Bromomethyl)-1-nitro-4-(trifluoromethyl)benzene (CAS 133605-28-4)
- Methyl 2-chloro-4-{4-[(piperidin-1-yl)carbonyl]phenyl}benzoate (CAS 1820712-06-8)
- Pancreatic Polypeptide (1-17)-(Ala31,Aib32)-Neuropeptide Y (18-36) (human) trifluoroacetate salt (CAS 313988-70-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com