Roxatidine Impurity 30 CAS CATO-C4X-121330
| CAS No. | CATO-C4X-121330 |
| Molecular Formula | C17H25ClN2O2 |
| Molecular Weight | 324.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Roxatidine Impurity 30 (CAS CATO-C4X-121330), a pharmacopoeial impurity reference standard (molecular formula C17H25ClN2O2, MW 324.85 g/mol) used for the identification and quantification of trace impurities in APIs.
Roxatidine Impurity 30 (C17H25ClN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Roxatidine Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H25ClN2O2 |
| Molecular Weight | 324.85 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Roxatidine Standards
- Roxatidine Impurity 31 (CAS CATO-C4X-121331)
- Roxatidine Impurity 15 (CAS CATO-C4X-121315)
- Roxatidine Impurity 33 (CAS CATO-C4X-121333)
- Roxatidine Impurity 12 (CAS CATO-C4X-121312)
- Roxatidine Impurity 28 (CAS CATO-C4X-121328)
- Roxatidine Impurity 37 (CAS CATO-C4X-121337)
- Roxatidine Impurity 38 (CAS CATO-C4X-121338)
- Roxatidine Impurity 79 (CAS CATO-C4X-121379)
Recommended Standards
- Tert-butyl 4-amino-4-(4-chlorobenzyl)piperidine-1-carboxylate (CAS 956460-41-6)
- Loratadine EP Impurity G (CAS 38092-89-6)
- Tert-butyl 4-(aminomethyl)-4-(4-chlorophenyl)piperidine-1-carboxylate (CAS 669068-16-0)
- Desloratadine Impurity 30 (CAS 183198-48-3)
- Deoxycholic acid Impurity 11 (CAS CATO-C4X-335911)
- Roflumilast Impurity C65 (CAS 162401-60-7)
- Rosuvastatin Impurity 185 (CAS CATO-C4X-1169185)
- 3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2096331-60-9)
- Edoxaban Impurity 59 (p-Toluenesulfonic acid) (CAS 2852734-45-1)
- 4-Propyl-2-azetidinone (CAS 22937-03-7)
- tert-Butyl (2-(6-cyano-4-formylpyridin-2-yl)ethyl)carbamate (CAS 1393543-11-7)
- 2,2,8-Trimethyl-4H-1,3-dioxino[4,5-c]pyridine-5-carboxaldehyde (CAS 6560-65-2)
- 2-(3-benzyloxyphenyl)-1-nitroethene 24550-32-1 (CAS 24550-32-1)
- Semaglutide impurity 98 (CAS CATO-C4X-222698)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com