Isavuconazole Impurity 76 Chloride DiHCl CAS CATO-C4X-123676
| CAS No. | CATO-C4X-123676 |
| Molecular Formula | C39H45F2N8O6S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Isavuconazole Impurity 76 Chloride DiHCl (CAS CATO-C4X-123676) is a certified pharmaceutical impurity reference standard with the molecular formula C39H45F2N8O6SHClCl and a molecular weight of 863.80 g/mol.
The molecular framework of Isavuconazole Impurity 76 Chloride DiHCl (C39H45F2N8O6SHClCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C39H45F2N8O6S 2*HCl Cl |
| Molecular Weight | 863.80 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 1 |
Related Isavuconazole Standards
- Isavuconazole Impurity 221 (CAS 1062201-83-5)
- Isavuconazole HCl (CAS 1121545-23-0)
- Isavuconazole Impurity 24 (CAS 1176988-44-5)
- Isavuconazole Impurity 33 (CAS 1180002-01-0)
- Isavuconazole Impurity 60 (CAS 123-73-9)
- Isavuconazole Impurity 62 (CAS 1286730-05-9)
- Isavuconazole-d4 (CAS 1346598-58-0)
- Isavuconazole Impurity N15 (CAS 1443-80-7)
Recommended Standards
- Clomifene EP Impurity C HCl (CAS 5635-70-1)
- Apixaban Impurity 37 (CAS 99585-01-0)
- Crizotinib Impurity 48 (CAS CATO-C4X-102548)
- 5-(Azetidin-3-yloxy)-2,2-dimethylpentanenitrile (CAS 1489808-73-2)
- (2S)-2-(1-Methylethyl)-1-[(4-methylphenyl)sulfonyl]aziridine (CAS 62596-65-0)
- 1,1,1-Trifluoro-4-(methylthio)butan-2-one (CAS 1341824-67-6)
- Methotrexate impurity 51 (CAS CATO-C4X-115451)
- Methyl 3-(2-iodophenyl)-3-oxopropanoate (CAS 676348-63-3)
- 5-Bromo-3-methyl-6-(phenylthio)pyrimidine-2,4(1H,3H)-dione (CAS 81077-92-1)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com