Sunitinib Impurity 59 CAS CATO-C4X-133359
| CAS No. | CATO-C4X-133359 |
| Molecular Formula | C23H20F2N4O2 |
| Molecular Weight | 422.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Sunitinib Impurity 59 (CAS CATO-C4X-133359) is a certified pharmaceutical impurity reference standard with the molecular formula C23H20F2N4O2 and a molecular weight of 422.43 g/mol.
Based on its molecular formula C23H20F2N4O2, Sunitinib Impurity 59 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 422.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C23H20F2N4O2 |
| Molecular Weight | 422.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Sunitinib Standards
- Sunitinib Impurity 64 (CAS CATO-C4X-133364)
- Sunitinib Impurity 70 (CAS CATO-C4X-133370)
- Sunitinib Impurity 2 (CAS 356068-99-0)
- Sunitinib Impurity 74 (CAS CATO-C4X-133374)
- Sunitinib Impurity 81 (CAS CATO-C4X-133381)
- Sunitinib Impurity N1 (CAS 2377533-92-9)
- Sunitinib-d10 (CAS 1126721-82-1)
- Sunitinib Impurity 65 (CAS CATO-C4X-133365)
Recommended Standards
- Benidipine Impurity 59 (CAS 61311-83-9)
- Irinotecan impurity 57 (CAS CATO-C4X-166757)
- Methyl 3-(2-{[(4-fluorophenyl)carbamoyl]carbonyl}-1H-pyrrol-1-yl)-1-benzothiophene-2-carboxylate (CAS 477872-80-3)
- Cabozantinib Impurity 18 (CAS CATO-C4X-201818)
- Ledipasvir Impurity 55 (CAS CATO-C4X-331355)
- Diclofenac impurity 9 (CAS CATO-C4X-16149)
- Benidipine Impurity 70 (CAS CATO-C4X-112070)
- 4-(Aminomethyl)indolin-2-one hydrochloride (CAS 264272-68-6)
- 2-METHYL-5,6,7,8-TETRAHYDROPYRIDO[4,3-D]PYRIMIDINE (CAS 676994-65-3)
- (Z)-3-(((4-chlorobenzoyl)oxy)imino)-1-(2,4-dichlorobenzyl)indolin-2-one (CAS 320419-58-7)
- Levocarnitine Impurity 40 (CAS CATO-C4X-129240)
- 4-Ethyl-2-fluorobenzoic acid (CAS 37135-28-7)
- 1-(4-(1,1,2,3,3,3-Hexafluoropropoxy)phenyl)ethan-1-one (CAS 933673-41-7)
- Prolactin-Releasing Peptide (1-31) (human) (CAS 215510-22-8)
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